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Proteomicsp-FADD-CD8+T cell axis determines hepatocellular carcinoma response to immune checkpoint inhibitors
The heterogenicity of hepatocellular carcinoma (HCC) remains a key obstacle in turning the majority of ‘immune-cold’ tumors ‘hot’ for effective immune checkpoint inhibitors (ICIs). Through analyzing the naturally-existed ‘hot’ HCC variants, we identified fas-associated death domain (FADD) as a key m...
ORGANISM(S): Homo sapiens (Human) 
2025-07-07 | PXD057519 | Pride
Hcc Fadd Hepg2 
UnknownBedtime smart device usage and accelerometer-measured sleep outcomes in children and adolescents.
Not available
S-EPMC8856998 | biostudies-literature
UnknownExperimental infection of Z:ZCLA Mongolian gerbils with human hepatitis E virus.
Not available
S-EPMC4299338 | biostudies-literature
UnknownEffect of Chang'an decoction on ulcerative colitis by regulating T helper 17 cells and regulatory T cellsRab27 in the p53/high mobility group box 1 pathway.
Not available
S-EPMC12453985 | biostudies-literature
MetabolomicsSex-specific metabolic shifts in plasma of COVID-19 patients after cure
Metabolic profiling in COVID-19 patients has been associated with disease severity, but there is no report on sex-specific metabolic changes in discharged survivors. Herein we used an integrated approach of LC-MS-and GC-MS-based untargeted metabolomics to analyze plasma metabolic characteristics in ...
2022-01-10 | MTBLS2224 | MetaboLights
UnknownPotent immunomodulation and angiogenic effects of mesenchymal stem cells versus cardiomyocytes derived from pluripotent stem cells for treatment of heart failure.
Not available
S-EPMC6407247 | biostudies-literature
UnknownSignificance of the myxovirus resistance A (MxA) gene -123C>a single-nucleotide polymorphism in suppressed interferon beta induction of severe acute respiratory syndrome coronavirus infection.
Not available
S-EPMC7109798 | biostudies-literature
UnknownInhibition of cardiomyocytes differentiation of mouse embryonic stem cells by CD38/cADPR/Ca2+ signaling pathway.
Not available
S-EPMC3471724 | biostudies-literature
ProteomicsAnti-Toxoplasma gondii effect of vorinostat in vitro and in vivo
Toxoplasma gondii is an important pathogenic protozoon that infects up to one-third of the world's population. In immunocompetent individuals, the infection generally is asymptomatic. However, in immunocompromised patients, the infection can lead to severe and fatal complications. This is due to the...
ORGANISM(S): Toxoplasma Gondii Rh-88 
2024-07-17 | PXD053997 |
UnknownPreliminary effectiveness and feasibility of an integrated hope techniques and narrative-based card game intervention for pediatric cancer patients in China: a randomized controlled trial.
Not available
S-EPMC12315444 | biostudies-literature
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