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MetabolomicsResveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
Resveratrol (RESV) is a plant polyphenol, which is thought to have beneficial metabolic effects in laboratory animals as well as in humans. Following oral administration, RESV is immediately catabolized, resulting in low bioavailability. This study compared RESV metabolites and their tissue distribu...
MTBLS127 | MetaboLights
MetabolomicsDifferent dose exposure of OPC-163493 on HepG2 cells (part-I)
Not available
ORGANISM(S): Homo sapiens 
ST001135 | MetabolomicsWorkbench
MetabolomicsSingle cell lipidome analysis of phosphatidylcholines and spingomyelins from HepG2 and C2C12 cells
Not available
ORGANISM(S): Homo sapiens 
ST002366 | MetabolomicsWorkbench
MetabolomicsFructosamine-3-kinase (FN3K) KO in HepG2 liver cancer cells
Not available
ORGANISM(S): Homo sapiens 
ST001375 | MetabolomicsWorkbench
GenomicsHNF4A-binding sites in HepG2 hepatoblastoma cells treated with TGF-beta
Specific regulation of target genes by transforming growth factor-β (TGF-β) in a given cellular context is determined in part by transcription factors and cofactors that interact with the Smad complex. In the present study, we determined Smad2 and Smad3 (Smad2/3) binding regions in the promoters of ...
ORGANISM(S): Homo sapiens 
2011-06-08 | E-GEOD-28845 | biostudies-arrayexpress
TranscriptomicsExpression Profiles of HepG2 cells treated with 22 compounds and solvent controls
The transcriptomics changes induced in the human liver cell line HepG2 by 17 hepatotoxic compounds, 5 non-hepatotoxic compounds and solvent controls after treatment for 24h The study investigated differential gene expression in HepG2 cell line mRNA following 24 hours of exposure to 17 hepatotoxic co...
ORGANISM(S): Homo sapiens 
2014-02-14 | E-GEOD-51952 | biostudies-arrayexpress
MetabolomicsTemporal metabolomic responses of cultured HepG2 liver cells to high fructose and high glucose exposures (part II)
Not available
ORGANISM(S): Homo sapiens 
ST000380 | MetabolomicsWorkbench
MetabolomicsCyclobutene- and cyclobutane-functionalized fatty acids as novel biochemical probes of structure and function in HepG2 cells
Not available
ORGANISM(S): Homo sapiens 
ST000241 | MetabolomicsWorkbench
TranscriptomicsGene expression profiles for genetically engineered human hepatoma HepG2/8F_HS cells with or without heat treatment, cultured as monolayer or spheroids
We developed genetically engineered HepG2/8F_HS cells, in which eight liver-enriched transcription factor (LETF) genes—hepatocyte nuclear factor (HNF)-1α, HNF-1β, HNF-3β, HNF-4α, HNF-6, CCAAT/enhancer binding protein (C/EBP)-α, C/EBP-β and C/EBP-γ— under the control of TRE/PCMVmin promoter were intr...
ORGANISM(S): Homo sapiens 
2022-04-04 | E-MTAB-11486 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of control and TNFalpha treated HepG2 cells
The proinflammatory cytokine, TNFalpha is critical in maintaining liver homeostasis since it is a major determiner of hepatocyte life and death. Considering this, gene transcription profiling was examined in control and TNFalpha treated HepG2 cells. Results indicated that TNFalpha could significantl...
ORGANISM(S): Homo sapiens 
2010-03-04 | E-GEOD-12161 | biostudies-arrayexpress
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