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TranscriptomicsEvolution of Context Dependent Regulation by Expansion of Feast/Famine Regulatory Proteins [ChIP-chip]
Chromatin immunoprecipitation and microarray hybridization (ChIP-chip) experiments were carried out for all 8 FFRPs in H. salinarum NRC-1. To study the FFRP localization in both nutrient-replete and -deplete conditions, all strains were grown in CDM and genomic DNA of samples was harvested in both e...
ORGANISM(S): Halobacterium sp. NRC-1 
2014-10-03 | E-GEOD-62051 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse macrophage responses to all-trans retinoic acid between wild type and NCoR-/- mice
Comparison of mouse macrophage responses to all-trans retinoic acid between wild-type and NCoR-/- mice.
ORGANISM(S): Mus musculus 
2006-11-06 | E-MEXP-37 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse macrophage responses to lipopolysaccharide (LPS) and 12-o-tetradecanoylphorbol-13-acetate (TPA) in wild type and NcoR-/- mice
Comparison of mouse macrophage responses to lipopolysaccharide (LPS) and 12-o-tetradecanoylphorbol-13-acetate (TPA) between wild-type and NcoR-/- mice.
ORGANISM(S): Mus musculus 
2006-11-06 | E-MEXP-38 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse macrophage responses to 12-o-tetradecanoylphorbol-13-acetate (TPA), lipopolysaccharide (LPS), and LPS plus dexamethasone between wild type and NCoR-/- mice
Comparison of mouse macrophage responses to 12-o-tetradecanoylphorbol-13-acetate (TPA), lipopolysaccharide (LPS), and LPS plus dexamethasone between wild-type and NCoR-/- mice.
ORGANISM(S): Mus musculus 
2004-08-01 | E-MEXP-39 | biostudies-arrayexpress
TranscriptomicsEvolution of Context Dependent Regulation by Expansion of Feast/Famine Regulatory Proteins
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Halobacterium sp. NRC-1 
2014-10-03 | E-GEOD-62052 | biostudies-arrayexpress
TranscriptomicsMetastable pluripotent states in NOD mouse derived ES cells
Embryonic stem (ES) cells are isolated from the inner cell mass (ICM) of developing blastocysts, whereas epiblast stem cells (EpiSCs) are derived from the post-implantation epiblast and are characterized by a restricted developmental potential. Although certain mouse strains, such as the non-obese d...
ORGANISM(S): Mus musculus 
2009-04-09 | E-GEOD-15603 | biostudies-arrayexpress
TranscriptomicsEvolution of Context Dependent Regulation by Expansion of Feast/Famine Regulatory Proteins
We validated context dependent regulation by two FFRPs AsnC and VNG1237C by deleting the FFRP and testing the effect on downstream target genes. For validtion of AsnC condition specific regulation we grew wild-type and delta-AsnC in the presence of 4mM paraquat (PQ) and samples at 1 and 160 minutes ...
ORGANISM(S): Halobacterium sp. NRC-1 
2014-10-02 | E-GEOD-61975 | biostudies-arrayexpress
ProteomicsTHE PHARMACOLOGICAL RESCUE OF CFTR BY LUMACAFTOR (VX-809) IN THE CYSTIC FIBROSIS BRONCHIAL EPITHELIUM IS ASSOCIATED WITH AN EXTENSIVE REORGANIZATION OF MITOCHONDRIA.
Cystic Fibrosis (CF) is a genetic disorder CF is caused by mutations of the gene encoding for the cystic fibrosis transmembrane conductance regulator protein (CFTR), a transmembrane anion channel expressed at the apical membrane of several organs, including the epithelial cells of the airway. CFTR m...
ORGANISM(S): Homo sapiens (Human) 
2022-08-11 | PXD028355 | Pride
Vx-809 Proteomics Cfbe41o- cells Cystic fibrosis 
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS390 | MetaboLights
TranscriptomicsDerivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations
The presence of two active X chromosomes (XaXa) is a hallmark of the ground state of pluripotency specific to murine embryonic stem cells (ESCs). Human ESCs invariably exhibit signs of X chromosome inactivation (XCI) and are considered developmentally more advanced than their murine counterparts....
ORGANISM(S): Homo sapiens 
2010-11-10 | E-GEOD-20937 | biostudies-arrayexpress
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