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ProteomicsProteomic analysis of laser-microdissected murine fetal glomeruli
Alteration of fetal kidney morphogenesis in diabetic pregnancies is poorly described, especially changes in the extracellular matrix (ECM) and glomerular basement membrane (GBM) during glomerulogenesis. Addressing the ECM proteome, or matrisome, in mouse fetal glomeruli in a healthy and diabetic env...
ORGANISM(S): Mus musculus (Mouse) 
2021-10-13 | PXD025911 | Pride
Mouse Tandem mass spectrometry Glomerulus Laser microdissection microscopy Glomerular basement membrane Extracellular matrix 
ProteomicsProteomic analysis of healthy and hyperglycemic murine fetal kidneys
Alteration of kidney morphogenesis in diabetic pregnancies is poorly described, especially changes in the extracellular matrix (ECM) and glomerular basement membrane (GBM during glomerulogenesis. Addressing the ECM proteome, or matrisome, in the mouse fetal kidney in a healthy and diabetic environme...
ORGANISM(S): Mus musculus (Mouse) 
2021-10-13 | PXD025874 | Pride
Mass spectrometry Basement membrane Enrichment Kidney Extracellular matrix Diabetes 
ProteomicsProteomic analysis of induced pluripotent stem cell-derived kidney organoids
Kidney organoids were generated from a control iPSC line using a previously published protocol (https://doi.org/10.1038/nprot.2016.098). Organoids were collected at three timepoints during the protocol (day 14, 18 and 25) and prepared for proteomic analyses. The focus of the study was to define the ...
ORGANISM(S): Homo sapiens (Human) 
2021-10-13 | PXD025838 | Pride
Mass spectrometry Basement membrane Kidney organoid Enrichment Kidney Extracellular matrix 
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