Sort   by:  
 Page size 
TranscriptomicsTranscription Factor Network Specifying Inhibitory versus Excitatory Neurons in the Dorsal Spinal Cord [RNA-Seq]
The proper balance of excitatory and inhibitory neurons is crucial to normal processing of somatosensory information in the dorsal spinal cord. Two neural basic helix-loop-helix transcription factors, Ascl1 and Ptf1a, are essential for generating the correct number and sub-type of neurons in multipl...
ORGANISM(S): Mus musculus 
2014-06-13 | E-GEOD-55831 | biostudies-arrayexpress
UnknownOverall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC4672027 | biostudies-literature
TranscriptomicsAnalysis of the Cerebral Cortex and Hippocampus Transcriptome Reveals Unique Molecular Changes in the Ts1Cje Mouse Model of Down Syndrome
Down syndrome is characterized by a complex phenotype that includes developmental disabilities and congenital anomalies. The molecular origin of these abnormalities is poorly understood. The objective of this study is to analyze whole transcriptome changes in the cortex and hippocampus of the Ts1Cje...
ORGANISM(S): Mus musculus 
2013-09-05 | E-GEOD-49635 | biostudies-arrayexpress
GenomicsTranscription Factor Network Specifying Inhibitory versus Excitatory Neurons in the Dorsal Spinal Cord [ChIP-Seq]
The proper balance of excitatory and inhibitory neurons is crucial to normal processing of somatosensory information in the dorsal spinal cord. Two neural basic helix-loop-helix transcription factors, Ascl1 and Ptf1a, are essential for generating the correct number and sub-type of neurons in multipl...
ORGANISM(S): Mus musculus 
2014-06-13 | E-GEOD-55840 | biostudies-arrayexpress
TranscriptomicsAnalysis of the Fetal and Neonatal Transcriptomic and Neurocognitive Phenotype in the Ts1Cje Mouse Model of Down syndrome
Down syndrome is characterized by a complex phenotype that includes developmental disabilities and congenital anomalies emerging during fetal life. The molecular origin of these abnormalities is poorly understood. Despite the evidence of prenatal onset of the phenotype, most therapeutic trials have ...
ORGANISM(S): Mus musculus 
2014-11-15 | E-GEOD-62538 | biostudies-arrayexpress
TranscriptomicsChanges in Mouse Uterine Transcriptome in Estrus and Proestrus
The potential for xenoestrogens and other environmental chemicals to alter female reproductive function calls for the study of their affects on endogenous hormone-regulated gene expression pathways during uterine tissue remodeling which occurs as part of the menstrual/estrus cycle. However, our kno...
ORGANISM(S): Mus musculus 
2013-06-07 | E-GEOD-43064 | biostudies-arrayexpress
TranscriptomicsIn Vitro Transcriptome Analysis of Cobalt Boride Nanoparticles on Human Pulmonary Alveolar Cells
In this study, we first characterized commercially available cobalt boride (Co2B) nanoparticles (NPs) using X-ray crystallography (XRD), transmission electron microscope (TEM), scanning electron microscope (SEM) and energy-dispersive X-ray spectroscopy (EDX) techniques. Next, we selected 3-(4,5-dime...
ORGANISM(S): Homo sapiens 
2021-08-28 | E-MTAB-9035 | biostudies-arrayexpress
TranscriptomicsExendin-4, a glucagon-like peptide-1 receptor agonist prevents mTBI-induced changes in hippocampus gene expression and memory deficits in mice
Traumatic brain injury (TBI) is a global problem reaching near epidemic numbers that manifests clinically with cognitive problems that decades later may result in dementias like Alzheimer’s disease (AD). Presently, little can be done to prevent ensuing neurological dysfunctions by pharmacological me...
ORGANISM(S): Mus musculus 
2012-10-17 | E-GEOD-41345 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse brain regions (bed nucleus of the stria terminalis, hippocampus, hypothalamus, periaqueductal gray, and pituitary gland) in six mouse strains (129S6/SvEvTac, A/J, C57BL/6J, C3H/HeJ, DBA/2J, and FVB/NJ)
Gene expression patterns were determined from five brain regions (bed nucleus of the stria terminalis, hippocampus, hypothalamus, periaqueductal gray, and pituitary gland) in six mouse strains (129S6/SvEvTac, A/J, C57BL/6J, C3H/HeJ, DBA/2J, and FVB/NJ). At least two replicate samples per brain regio...
ORGANISM(S): Mus musculus 
2009-09-16 | E-GEOD-4734 | biostudies-arrayexpress
TranscriptomicsTranscriptome Profiling of Hippocampal CA1 After Early Life Seizure-Induced Preconditioning May Elucidate New Genetic Therapies for Epilepsy
Injury of the CA1 subregion induced by a single injection of kainic acid (1M-CM-^WKA) is attenuated when juvenile animals (P20) have a history of two sustained neonatal seizures on P6 and P9. To identify gene candidates involved in the spatially protective effects produced by early life conditioning...
ORGANISM(S): Rattus norvegicus 
2013-02-14 | E-GEOD-44031 | biostudies-arrayexpress
Sort   by:  
 Page size