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TranscriptomicsThe Influence of Sleep Deprivation on Hippocampal CA1 Gene Expression: Relation to Stress and Aging
Sleep deprivation (SD) in young adults is associated with metabolic, stress and cognitive responses that are also characteristic of brain aging. Given that sleep architecture changes with age, including increased fragmentation and decreased slow wave activity, it seems reasonable to investigate pote...
ORGANISM(S): Rattus norvegicus 
2012-07-16 | E-GEOD-34424 | biostudies-arrayexpress
TranscriptomicsTranscriptome In Vivo Analysis (TIVA) of spatially defined single cells in intact live mouse and human brain tissue
Transcriptome profiling is an indispensable tool in advancing the understanding of single cell biology, but depends upon methods capable of isolating mRNA at the spatial resolution of a single cell. Current capture methods lack sufficient spatial resolution to isolate mRNA from individual in vivo re...
ORGANISM(S): Mus musculus 
2014-01-12 | E-GEOD-52525 | biostudies-arrayexpress
Transcriptomicsgene expression in human subcutaneous adipose tissue after CLA intervention
Iisomer-specific effects of conjugated linoleic (CLA) supplementation on gene expression with particular consideration of the PPAR 2 Pro12Ala SNP in human adipose tissue. Effect of CLA supplementation on genome wide gene expression in adipose tissue biopsies from 5 PPARg2 Ala12Ala and 5 PPARg2 Pro12...
ORGANISM(S): Homo sapiens 
2009-09-01 | E-GEOD-16615 | biostudies-arrayexpress
TranscriptomicsMicroarray profiling of polyploid macrophage progeny
To explore how bacterial lipoproteins (i.e. TLR2 ligands) increased macrophage ploidy via mitotic defects, we performed global analysis of cell cycle gene expression changes induced by bacterial lipoproteins. FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that represents the N-terminal part of th...
ORGANISM(S): Mus musculus 
2016-10-27 | E-MTAB-5085 | biostudies-arrayexpress
UnknownMenke-Hennekam syndrome; delineation of domain-specific subtypes with distinct clinical and DNA methylation profiles.
Not available
S-EPMC11040166 | biostudies-literature
UnknownA Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts.
Not available
S-EPMC8500913 | biostudies-literature
UnknownGenomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.
Not available
S-EPMC7077032 | biostudies-literature
UnknownDissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.
Not available
S-EPMC8851871 | biostudies-literature
UnknownSex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.
Not available
S-EPMC8458480 | biostudies-literature
UnknownMapping the human genetic architecture of COVID-19.
Not available
S-EPMC8674144 | biostudies-literature
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