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UnknownOverall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC4672027 | biostudies-literature
TranscriptomicsIdentification of the miRNA targetome in hippocampal neurons using RIP-seq
We established a neuron-specific Argonaute2:GFP-RNA immunoprecipitation followed by high throughput sequencing (AGO2-RIP-seq) to analyse the regulatory role of miRNAs in mouse hippocampal neurons. Using this technique, we identified more than two thousand miRNA target genes in hippocampal neurons, r...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-65543 | biostudies-arrayexpress
TranscriptomicsBehaviorally activated mRNA expression profiles produce signatures of learning and enhanced inhibition in aged rats with preserved memory
Aging is often associated with cognitive decline, but many elderly individuals maintain a high level of function throughout life. Here we studied outbred rats, which also exhibit individual differences across a spectrum of outcomes that includes both preserved and impaired spatial memory. Previous w...
ORGANISM(S): Rattus norvegicus 
2013-12-16 | E-GEOD-47867 | biostudies-arrayexpress
TranscriptomicsDistinct cognitive effects and underlying transcriptome changes upon inhibition of individual miRNAs in hippocampal neurons
MicroRNAs (miRNA) are small, non-coding RNAs mediating post-transcriptional regulation of gene expression. miRNAs have recently been implicated in hippocampus-dependent functions such as learning and memory, although the roles of individual miRNAs in these processes remain largely unknown. Here, we ...
ORGANISM(S): Mus musculus 
2016-03-01 | E-GEOD-68884 | biostudies-arrayexpress
ProteomicsEffect of Cpd1 on melanoma proteome
Investigation of the time dependent effect of Cpd1 (small molecule interactor) on the proteome composition of melanoma WM3734 line by label-free quantification using mass spectrometry. The goal was to identify which protein abundances are increased upon treatment with Cpd1. Melanoma cell line WM3734...
ORGANISM(S): Homo sapiens (Human) 
2022-03-14 | PXD008757 | Pride
Jarid1b Cpd1 Melanoma cell line wm3734 
TranscriptomicsTransposable element expression at unique loci in single cells with CELLO-seq
We introduce a novel method (CELLO-seq) for long-read RNA sequencing at single cell resolution. CELLO-seq allows for full-length RNA sequencing and enables measurement of allelic, isoform and Transposable Element (TE) expression at unique loci. We use CELLO-seq to assess the widespread expression of...
ORGANISM(S): Homo sapiens 
2020-10-01 | E-MTAB-9577 | biostudies-arrayexpress
UnknownPersister state-directed transitioning and vulnerability in melanoma.
Not available
S-EPMC9160289 | biostudies-literature
UnknownEnhancing cognitive performance prediction by white matter hyperintensity connectivity assessment.
Not available
S-EPMC11629703 | biostudies-literature
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