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TranscriptomicsTranscription profiling of mouse high and low exploratory genetically identical animals
Genetically identical inbred mice exhibit substantial stable individual variability in exploratory behavior. We used microarrays to look at gene expression differences in the hippocampus in female mice separated by stable differences in exploratory behavior Experiment Overall Design: Balb c/J offsp...
ORGANISM(S): Mus musculus 
2008-10-26 | E-GEOD-11680 | biostudies-arrayexpress
TranscriptomicsAlzheimer's disease and the normal aged brain (steph-affy-human-433773)
Information about the genes that are preferentially expressed during the course of Alzheimer’s disease (AD) could improve our understanding of the molecular mechanisms involved in the pathogenesis of this common cause of cognitive impairment in older persons, provide new opportunities in the diagnos...
ORGANISM(S): Homo sapiens 
2006-07-10 | E-GEOD-5281 | biostudies-arrayexpress
UnknownCopper in Wood Preservatives Delayed Wood Decomposition and Shifted Soil Fungal but Not Bacterial Community Composition.
Not available
S-EPMC6365821 | biostudies-literature
TranscriptomicsTranscription profiling of mouse Balb c/J offspring subjected to postnatal handling vs. controls
Postnatal handling in rodents leads to decreased anxiety-like behavior in adulthood. We used microarrays to look at gene expression differences in the CA1 region of the hippocampus in female mice subjected to postnatal handling compared to controls. Experiment Overall Design: Balb c/J offspring wer...
ORGANISM(S): Mus musculus 
2008-10-26 | E-GEOD-11679 | biostudies-arrayexpress
UnknownPTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma.
Not available
S-EPMC10445595 | biostudies-literature
TranscriptomicsTranscription profiling of mouse model of succinate semialdehyde dehydrogenase deficiency vs wild type litter mates reveals multiple myelin alterations
Succinate semialdehyde dehydrogenase (SSADH) deficiency is a rare autosomal recessive disorder effecting approximately 350 people around the world. Patients suffering from SSADH deficiency experience language acquisition failure, memory deficiencies, autism, increased aggressive behaviors, and seizu...
ORGANISM(S): Mus musculus 
2007-07-07 | E-GEOD-2866 | biostudies-arrayexpress
TranscriptomicsComparative profiling in 13 muscle disease groups
Summary: Genetic disorders of muscle cause muscular dystrophy, and are some of the most common inborn errors of metabolism. Muscle also rapidly remodels in response to training and innervation. Muscle weakness and wasting is important in such conditions as aging, critical care medicine, space flig...
ORGANISM(S): Homo sapiens 
2005-10-14 | E-GEOD-3307 | biostudies-arrayexpress
TranscriptomicsAutism and increased paternal age related changes in global levels of gene expression regulation
A causal role of mutations in genes encoding for multiple general transcription factors in neurodevelopmental disorders including autism suggested that alterations at the global level of gene expression regulation might also relate to disease risk in sporadic cases of autism. This premise can be tes...
ORGANISM(S): Homo sapiens 
2011-10-08 | E-GEOD-25507 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of Drosophila DNA to identify nucleosomes bound by RNA polymerase II
Crosslinked chromatin was digested with Micrococcal nuclease and immunopurified for Rpb3, a subunit of RNA Polyermase II. chIP'd DNA was hybridized to Drosophila tiling arrays and nucleosomes that were bound by Pol II were mapped.
ORGANISM(S): Drosophila melanogaster 
2008-05-20 | E-MEXP-1515 | biostudies-arrayexpress
UnknownElectronic Health Diary Campaigns to Complement Longitudinal Assessments in Persons With Multiple Sclerosis: Nested Observational Study.
Not available
S-EPMC9582921 | biostudies-literature
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