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TranscriptomicsCharacterization of perivascular MSC from the adult human brain
Brain perivascular cells have been recently identified as new mesodermal cell type of the human brain. These cells reside in the perivascular niche and were shown to have mesodermal and – to a lesser extend – tissue-specific differentiation potential. Mesenchymal stem cells (MSCs) are widely dis...
ORGANISM(S): Homo sapiens 
2015-11-03 | E-GEOD-62505 | biostudies-arrayexpress
TranscriptomicsDeep sequencing of the porcine endometrial transcriptome on day 12 of pregnancy
The porcine conceptus undergoes rapid differentiation and expansion of its trophoblastic membranes between Days 11 and 12 of gestation. Concomitant with trophoblast elongation, production of conceptus estrogen, the porcine embryonic pregnancy recognition signal increases. Conceptus attachment to the...
ORGANISM(S): Sus scrofa 
2013-10-31 | E-GEOD-48862 | biostudies-arrayexpress
TranscriptomicsMessenger RNA profiling of bovine endometrium during the estrous cycle using a custom-made cDNA array
The endometrium provides optimal conditions for the transport of sperm to the oviduct, to the site of fertilization, and later on for the reception of the embryo. To study these changes on the level of gene expression, a messenger RNA expression profiling of endometrium tissue samples collected from...
ORGANISM(S): Bos taurus 
2010-05-27 | E-GEOD-8337 | biostudies-arrayexpress
TranscriptomicsGenome-wide maps of chromatin changes uppon contextual fear conditioning in mice (RNA-seq)
The ability to form memories is a prerequisite for an organism’s behavioural adaptation to environmental changes. At the molecular level, the acquisition and maintenance of memory requires changes in chromatin modifications. In an effort to unravel the epigenetic network underlying both short- and...
ORGANISM(S): Mus musculus 
2015-11-24 | E-GEOD-74966 | biostudies-arrayexpress
GenomicsGenome-wide maps of chromatin changes uppon contextual fear conditioning in mice (meDIP-seq)
The ability to form memories is a prerequisite for an organism’s behavioural adaptation to environmental changes. At the molecular level, the acquisition and maintenance of memory requires changes in chromatin modifications. In an effort to unravel the epigenetic network underlying both short- and...
ORGANISM(S): Mus musculus 
2015-11-24 | E-GEOD-74965 | biostudies-arrayexpress
TranscriptomicsSex-specific effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene x environment interactions
prenatal stress response, genetic modification Background: Prenatal stress (PS) exposure has been shown to increase the risk for emotional disorders in later life. Furthermore, the serotonin transporter (5-HTT) genotype is suggested to exert a modulating effect on the association between early life ...
ORGANISM(S): Mus musculus 
2011-12-12 | E-GEOD-26025 | biostudies-arrayexpress
TranscriptomicsBovine endometrium at day 18 of pregnancy after transfer of in vitro produced or somatic cell nuclear transfer embryos
Although somatic cell nuclear transfer (SCNT) cloning is more efficient in bovine than in all other species tested so far, there is a high rate of pregnancy failure that has been linked to structural and functional abnormalities of the placenta. We tested the hypothesis that these changes may origin...
ORGANISM(S): Bos taurus 
2009-03-12 | E-GEOD-13663 | biostudies-arrayexpress
TranscriptomicsHuman adult white matter progenitor cells are multipotent neuroprogenitors identical to adult hippocampal progenitors
Adult neural progenitor cells (aNPCs) are a potential autologous cell source for cell replacement in neurologic diseases such as Parkinson’s disease or stroke or for cell-based gene therapy for neurometabolic diseases. Easy accessibility, long-term expandability and detailed characterization of ...
ORGANISM(S): Homo sapiens 
2016-06-10 | E-GEOD-47921 | biostudies-arrayexpress
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