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Polyamines are absolutely required for cell growth and proliferation. While polyamine depletion results in reversible cell cycle arrest, the actual mechanism of growth inhibition is still obscure. This work aimed at determining the cellular processes affected by reduction in the intracellular polyam...
ORGANISM(S): Mus musculus 
PolyA+ RNA samples from the twelve healthy human tissues were purchased from Clontech (Palo Alto, CA). Each RNA sample is typically composed of a pool of 10-25 individuals. The expression intensity of mRNA was assayed across five microarrays (Affymetrix GeneChips U95A–E). Please note GeneNote is now...
ORGANISM(S): Homo sapiens 
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ORGANISM(S): Homo sapiens 
We undertook an integrative technological approach to compare miRNA detection capability of three high-throughput commercial platforms. We artificially introduced human precursor, 2’-O-methyl modified and mature spiked-in miRNAs in a controlled fashion into native human placenta total RNA.
ORGANISM(S): Homo sapiens 
Retrograde signaling from axon to soma activates intrinsic regeneration mechanisms in lesioned peripheral sensory neurons; however, the links between axonal injury signaling and the cell body response are not well understood. Here, we used phosphoproteomics and microarrays to implicate ~900 phosphop...
ORGANISM(S): Rattus norvegicus 
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