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ProteomicsGenomic regions flanking E-box sites influence DNA binding specificity of bHLH transcription factors through DNA shape (different concentrations)
DNA sequence is a major determinant of the binding specificity of transcription factors (TFs) for their genomic targets. However, eukaryotic cells often express, at the same time, TFs with highly similar DNA binding motifs but distinct in vivo targets. Currently, it is not well understood how TFs wi...
ORGANISM(S): Saccharomyces cerevisiae 
2013-03-29 | E-GEOD-44436 | biostudies-arrayexpress
TranscriptomicsThe genome of the grape powdery mildew pathogen
Powdery mildew (Erysiphe necator) is a widespread and economically important disease of grapevines. Large quantities of fungicides are used for its control, accelerating the incidence of fungicide-resistance. A shotgun approach was applied to sequence and assemble the E. necator genome of five isola...
ORGANISM(S): Vitis vinifera 
2014-12-10 | E-GEOD-58958 | biostudies-arrayexpress
ProteomicsGenomic regions flanking E-box sites influence DNA binding specificity of bHLH transcription factors through DNA shape (validation)
DNA sequence is a major determinant of the binding specificity of transcription factors (TFs) for their genomic targets. However, eukaryotic cells often express, at the same time, TFs with highly similar DNA binding motifs but distinct in vivo targets. Currently, it is not well understood how TFs wi...
ORGANISM(S): Saccharomyces cerevisiae 
2013-03-29 | E-GEOD-44437 | biostudies-arrayexpress
ProteomicsAMCA chromophore tagging and 351 nm ultraviolet photodissociation enables de novo sequencing of E. coli proteome
Demonstration of novel experimental and computational pipeline for high performance de novo peptide sequencing. E. coli whole cell lysate is carbamylated to block lysine side chains, digested with trypsin (now active only at Arg residues), and N-terminally tagged with the chromophore AMCA. Three tec...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2016-03-10 | MSV000079571 | MassIVE
TranscriptomicsTranscription profiling of human cluster headache patients peripheral blood on Affymetrix arrays vs. controls
Background - Cluster headache (CH) is a primary neurovascular headache disorder characterized by attacks of excruciating pain accompanied by ipsilateral autonomic symptoms. CH pathophysiology is presumed to involve an activation of hypothalamic and trigeminovascular systems, but inflammation and imm...
ORGANISM(S): Homo sapiens 
2011-04-27 | E-MTAB-631 | biostudies-arrayexpress
UnknownGenomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape.
Not available
S-EPMC3640701 | biostudies-literature
Unknown(E)-N'-(5-Bromo-2-hy-droxy-benzyl-idene)-2-(4-isobutyl-phen-yl)propano-hydrazide.
Not available
S-EPMC3414297 | biostudies-literature
UnknownN'-[(E)-4-(Dimethyl-amino)-benz-ylidene]-2-(5-meth-oxy-2-methyl-1H-indol-3-yl)acetohydrazide.
Not available
S-EPMC3393912 | biostudies-literature
UnknownEvolutionary genomic analyses of canine E. coli infections identify a relic capsular locus associated with resistance to multiple classes of antimicrobials.
Not available
S-EPMC11337803 | biostudies-literature
UnknownSingle Chain Variable Fragments Produced in Escherichia coli against Heat-Labile and Heat-Stable Toxins from Enterotoxigenic E. coli.
Not available
S-EPMC4496030 | biostudies-literature
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