Sort   by:  
 Page size 
TranscriptomicsExpression profiling in dopaminergic brain structures of rats self-administering cocaine
Gene expression profiling in dopaminergic brain structures of rats self-administering cocaine. Effect of histone deacetylase inhibition We have shown that injection of the HDAC inhibitor trichostatin A (TsA) to rats is sufficient to decrease their motivation to self-administer cocaine. The aim of th...
ORGANISM(S): Rattus norvegicus 
2010-01-21 | E-GEOD-18055 | biostudies-arrayexpress
TranscriptomicsComparative transcriptomics of Rhizobium mesoamericanum STM3625, Cupriavidus taiwanensis LMG19424 and Burkholderia phymatum STM815 when induced by root exudates of Mimosa pudica
We analysed the transcriptomic response of 3 rhizobial symbionts of Mimosa pudica (Rhizobium mesoamericanum STM3625, Cupriavidus taiwanensis LMG19424 and Burkholderia phymatum STM815) when cultivated in a minimum culture medium (control condition) versus induced by root exudates of their host plant ...
ORGANISM(S): Cupriavidus taiwanensis LMG 19424 
2018-01-15 | E-MTAB-4144 | biostudies-arrayexpress
GenomicsSynergistic Activation of Inflammatory Cytokine Genes by Priming of Regulatory DNA Elements for Increased Transcription in Response to TLR Signaling
Synergistic activation of inflammatory cytokine genes by IFN-gamma and TLR signaling is important for innate immunity and inflammatory disease pathogenesis, but underlying mechanisms are not known. By obtaining over three billion bases of sequence from chromatin immunoprecipitated DNA, we generated ...
ORGANISM(S): Homo sapiens 
2013-09-20 | E-GEOD-43036 | biostudies-arrayexpress
ProteomicsAltered brain pathways following Chikungunya virus infection
A kinetic analysis of host proteome modifications in the brain of CHIKV-infected mice sampled before and after the onset of clinical symptoms was performed. The combination of 2D-DIGE and iTRAQ proteomic approaches, followed by mass spectrometry protein identification, revealed 177 significantly dif...
ORGANISM(S): Mus musculus (Mouse) 
2015-07-07 | PXD000736 | Pride
Brain Pathways modified Mouse Alphavirus Chikungunya virus Infection Itraq Pathogenesis 2d-dige 
TranscriptomicsRNAseq of roots and leaves of tender wheat (Triticum aestivum cv chinese Spring) during interactions with mycorhizal fungi (Funneliformis mossae) with and without a pathogen attack by Xanthomonas translucens
We monitored by RNAseq the transcriptomic response of roots and leaves of Triticum aestivum cv chinese Spring during a long term interaction with Funneliformis mossae (2 months) with or without a pathogen infection by infiltration of Xanthomonas translucens CFBP 2054. The control condition of roots ...
ORGANISM(S): Triticum aestivum 
2018-06-01 | E-MTAB-5898 | biostudies-arrayexpress
TranscriptomicsModulation of the TNF-induced macrophage response by synovial fibroblasts
Here we explored how the human macrophage response to tumor necrosis factor (TNF) is regulated by human synovial fibroblasts, the representative stromal cell type in the synovial lining of joints that become activated during inflammatory arthritis. Genome-wide transcriptome analysis (RNAseq) showed ...
ORGANISM(S): Homo sapiens 
2014-08-04 | E-GEOD-57723 | biostudies-arrayexpress
TranscriptomicsHierarchical synergy of Pten, p53 and Rb pathways in high-grade astrocytoma induced in adult brain
Mutations in the PTEN, TP53 and RB1 pathways are obligate events in the pathogenesis of human glioblastomas, the highest grade of astrocytoma. To investigate synergy between these tumor suppressors in mice, we induced various combinations of compound deletions conditionally in astrocytes and neural ...
ORGANISM(S): Mus musculus 
2011-03-23 | E-GEOD-22927 | biostudies-arrayexpress
Sort   by:  
 Page size