This study utilized metabolomics to analyze the metabolites of four host plants (Camptotheca acuminata, Populus deltoides, Prunus serrulate, and Taxodium distichum) and one non-host plant (Camphora officinarum) of fall webworm Hyphantria cunea.

Parasitism is a widespread source of mortality among marine microbial communities, with members of the diverse alveolate group Syndiniales being most prevalent and frequently identified in global omics studies. Despite their ubiquity, not much is known about Syndiniales parasite-host infection dy...

Modulating cell endocytosis activity to reduce host susceptibility to virus represents a promising strategy for antiviral drug development. In this study, we reveal that lactate transporter SLC16A3 as a critical host factor for reducing diverse virus invasion. By performing metabolomics, proteomi...

Malaria varies in severity, with complications ranging from uncomplicated to severe malaria. Severe malaria could be attributed to peripheral hyperparasitemia or cerebral malaria. The metabolic interactions between the host and Plasmodium species are yet to be understood during these inf...

The mechanistic role of the airway microbiome in chronic obstructive pulmonary disease (COPD) remains largely unexplored. We present a landscape of airway microbe-host interactions in COPD by an in-depth profiling of sputum metagenome, metabolome, host transcriptome and proteome from 99 COPD pati...

Introduction. Toxoplasma gondii is an obligate intracellular parasite with an exceptional capacity to colonize a broad range of host species and cell types. Successful infection depends on its ability to manipulate host metabolism, including lipid pathways that are essential for membrane biogenes...