Sort   by:  
 Page size 
TranscriptomicsmicroRNA profiling of female and male mouse pituitary gland across pubertal transition
The pituitary gland exhibits sex differences in its function. Diseases associated with dysregulation of the pituitary are also sex-biased in prevalence. Previous qPCR profiling of puberty-related genes in the pituitary gland revealed increasingly sex-biased expression of genes profiled across pubert...
ORGANISM(S): Mus musculus 
2022-10-12 | E-MTAB-9460 | biostudies-arrayexpress
ProteomicsSAINT_3727_JQ1_APMS_endoK562_P82_VS17_28AUG2018
This submission contains the mass spectrometry files for the manuscript by Lambert, Picaud et al. that describes the characterization of interactome changes induced by JQ1 on the BET proteins. This submission contains 16 files associated with endogenous IP-MS analysis of BRD2, BRD3 and BRD4 (IgG was...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-28 | MSV000082859 | MassIVE
ProteomicsSAINT_3726_JQ1_APMS_endoHEK293_P82_VS16_28AUG2018
This submission contains the mass spectrometry files for the manuscript by Lambert, Picaud et al. that describes the characterization of interactome changes induced by JQ1 on the BET proteins. This submission contains 16 files associated with endogenous IP-MS analysis of BRD2, BRD3 and BRD4 (IgG was...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-28 | MSV000082857 | MassIVE
ProteomicsUuskula_P112_VS2_TOP2B_BioID_15JUN2015
This submission contains the mass spectrometry files for the manuscript by Uuskula-Reimand et al. that investigates the interactome of TOP2B using BioID and its genomic binding profile. This submission contains 18 IDA files for the following baits: empty 3XFLAG control, GFP-BirA-FLAG control, NLS-Bi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-07-10 | MSV000079188 | MassIVE
TranscriptomicsRNA-seq of human mammary epithelial cell line MCF10A with RMRP/CCDC107/ARHGEF39-targeted CRISPR edits vs. scramble controls
The purpose of these experiments was to validate the role of a frequently mutated regulatory element bound by TOP2B using a functional genomics approach. Specifically, CRISPR/Cas9 was employed to selectively target the promoter of RMRP and non-coding regions of CCDC107 and ARHGEF39.
ORGANISM(S): Homo sapiens 
2025-01-01 | E-MTAB-14611 | biostudies-arrayexpress
GenomicsChIP-seq of CTCF, RAD21, and TOP2B binding sites in three human tissue samples with hepatocellular carcinoma
The roles of topoisomerases in somatic mutagenesis in cancer are poorly understood and their DNA-binding landscape remains largely unmapped. Here we generated genome-wide DNA-binding maps of TOP2B, CTCF, and RAD21 in human hepatocellular carcinoma samples.
ORGANISM(S): Homo sapiens 
2024-02-01 | E-MTAB-13301 | biostudies-arrayexpress
ProteomicsLambert_BRD_SAINT2307_JQ1_APMS_time_course_TripleTOF_P82_VS5
This submission contains the mass spectrometry files for the manuscript by Lambert, Picaud et al. that describes the characterization of interactome changes induced by JQ1 on the BET proteins. More precisely, files used in the SAINT express task 2307 are in this dataset. The AP-MS experiments involv...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-25 | MSV000081006 | MassIVE
TranscriptomicsRNA sequencing of sperm extracted from the epididymis in naked mole-rat subordinates, naked mole-rat ex-subordinates, and mice
Naked mole-rat show a strong phenotype of sperm hypo-motility and abnormal morphology. Comparative genomic analyses in our study presenting the telomere-to-telomere genome for the naked mole-rat identified several sperm-gene relaxation and sperm-gene loss events in the NMR. To test the transcriptomi...
ORGANISM(S): Mus musculus 
2026-07-31 | E-MTAB-17270 | biostudies-arrayexpress
GenomicsONT R10.4-Lsk sequencing of a naked mole-rat male subordinate. Sheared kidney, unsheared kidney, and brain samples
Two PacBio Hifi sequencing runs from the kidney of a single male NMR sample used to make the mHetGla4.1.primary genome assembly. Specifically, we assembled a second NMR genome from an unrelated male of a separate captive colony in Toronto, Canada, using PacBio HiFi (155.8 Gb, read N50 = 11.45 Kb) an...
ORGANISM(S): Heterocephalus glaber 
2026-08-06 | E-MTAB-17334 | biostudies-arrayexpress
GenomicsPacbio Hifi sequencing of a male cape dune mole-rat kidney sample
One PacBio Hifi sequencing run from the kidney of a single male CDMR (Bathyergus suillus) sample used to make the mBatSui1.1.primary genome assembly as an evolutionary comparator to our telomere-to-telomere naked mole-rat genome assembly. Specifically, we assembled a CDMR from a wild-derived sample ...
ORGANISM(S): Bathyergus suillus 
2026-08-05 | E-MTAB-17312 | biostudies-arrayexpress
Sort   by:  
 Page size