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ProteomicsMonolaurin confers a protective effect against porcine epidemic diarrhea virus infection in piglets by regulating the interferon pathway
Porcine epidemic diarrhea virus (PEDV) has reemerged as the main pathogen of piglets due to its high mutation feature. Monolaurin (ML) is a natural compound with a wide range of antibacterial and antiviral activities. However, the role of ML in PEDV infection is still unknown. This study aimed to ev...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-02-16 | PXD029561 | Pride
Infection. Interferon Monolaurin Piglets Porcine epidemic diarrhea virus 
TranscriptomicsSurvival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3b phosphorylation
Platelet-derived growth factor-CC (PDGF-CC) is the third member of the PDGF family discovered after more than two decades of studies on the original members of the family, PDGF-AA and PDGF-BB. The biological function of PDGF-CC remains largely to be explored. We report here a novel finding that PDGF...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-19207 | biostudies-arrayexpress
ProteomicsMetabolic Reprogramming in the Enterocytes of Neonatal Piglets Infected with Porcine Epidemic Diarrhea Virus: Integrated Omics and Multi-Batch Analysis Highlight Alterations in Lipid Metabolism and Potential Therapeutic Targets
Our research team recently investigated the role of PEDV on piglet intestinal metabolism. We conducted several independent animal experiments and collected the samples for transcriptomics and proteomics. Our purpose is to identify and validate prospective targets for both diagnostic and therapeutic ...
ORGANISM(S): Sus Scrofa Sus Scrofa Domesticus 
2026-02-27 | PXD075013 |
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