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TranscriptomicsLack of hepatic response of microRNA in mice following DB[a,h]A exposure (Agilent miRNA)
Dibenzo[a,h]anthracene DB[a,h]A is a polycyclic aromatic hydrocarbon potent carcinogen. Few studies have investigated the role of DB[a,h]A on mRNA and miRNA expression. In this study a 10-week old male MutaTM Mouse were exposed to 6.25, 12.5, and 25 mg/kg/day DB[a,h]A by oral gavage for 28 cons...
ORGANISM(S): Mus musculus 
2013-07-02 | E-GEOD-35195 | biostudies-arrayexpress
TranscriptomicsLack of hepatic response of microRNA in mice following DB[a,h]A exposure (Agilent expression)
Dibenzo[a,h]anthracene DB[a,h]A is a polycyclic aromatic hydrocarbon potent carcinogen. Few studies have investigated the role of DB[a,h]A on mRNA and miRNA expression. In this study a 10-week old male MutaTM Mouse were exposed to 6.25, 12.5, and 25 mg/kg/day DB[a,h]A by oral gavage for 28 cons...
ORGANISM(S): Mus musculus 
2013-07-02 | E-GEOD-35215 | biostudies-arrayexpress
TranscriptomicsLack of hepatic response of microRNA in mice following DB[a,h]A exposure
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-07-02 | E-GEOD-35509 | biostudies-arrayexpress
TranscriptomicsPulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage
Polycyclic aromatic hydrocarbons (PAHs) are widely distributed, carcinogenic environmental contaminants produced as a consequence of the incomplete combustion of fossil fuels. Benzo[a]pyrene (BaP) is a very extensively studied prototypical PAH. We recently reported a complete lack of change in micro...
ORGANISM(S): Mus musculus 
2011-10-03 | E-GEOD-24751 | biostudies-arrayexpress
ProteomicsMolecular changes during extended endocrine treatment of breast cancer
Sequential patient-matched samples treated with extended neoadjuvant therapy were studied. Samples were classified as pre-treatment (timepoint1, <0 days), early-on treatment (timepoint2, 0-120 days) and long-term treatment (timepoint4, >120 days).
ORGANISM(S): Homo sapiens (Human) 
2019-02-27 | PXD009328 | Pride
Letrozole Dormancy Sequential samples Breast cancer 
TranscriptomicsAdult mouse liver following benzo(a)pyrene (BaP) treatment: miRNA and mRNa profiling
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2010-10-18 | E-GEOD-18841 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling in male and female chicken embryonic gonads during sexual differentiation
MicroRNAs (miRNAs) are a highly conserved class of small RNAs which function in a sequence-specific manner to post-transcriptionally regulate expression of target genes. Tissue-specific miRNA expression studies have discovered numerous functions for miRNAs in various aspects of embryonic developmen...
ORGANISM(S): Gallus gallus 
2010-05-18 | E-GEOD-13154 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells
The human liver contains multiple cell types whose epigenetic patterns are undetermined. We examined the promoter methylome of purified and uncultured hepatic stellate cells (HSCs), hepatocytes (HEPs) and liver sinusoidal endothelial cells (LSECs), by methylated DNA immunoprecipitation (MeDIP) and a...
ORGANISM(S): Homo sapiens 
2015-12-21 | E-GEOD-66796 | biostudies-arrayexpress
MetabolomicsHost autophagy mediates organ wasting and nutrient mobilization for tumor growth
During tumor growth-when nutrient and anabolic demands are high-autophagy supports tumor metabolism and growth through lysosomal organelle turnover and nutrient recycling. Ras-driven tumors additionally invoke non-autonomous autophagy in the microenvironment to support tumor growth, in part through ...
2021-09-24 | MTBLS2771 | MetaboLights
TranscriptomicsLack of hepatic response of microRNA in mice following chronic benzo(a)pyrene exposure (gene expression)
Benzo[a]pyrene (BaP) is a very extensively studied prototypical polycyclic aromatic hydrocarbons (PAHs). Previous work in our laboratory showed no changes of microRNA (miRNA) expression in liver following a 3 days exposure to BaP, suggesting a lack of miRNA transcriptional responses to aryl hydrocar...
ORGANISM(S): Mus musculus 
2011-10-18 | E-GEOD-24907 | biostudies-arrayexpress
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