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UnknownGenome Sequencing Technologies and Nursing: What Are the Roles of Nurses and Nurse Scientists?
Not available
S-EPMC5334658 | biostudies-literature
TranscriptomicsTargeting H3K4 methylation as a therapeutic strategy for Huntington's disease (RNA-seq)
Transcriptional dysregulation is an early feature of Huntington's disease (HD). We observed gene-specific changes in H3K4me3 at transcriptionally repressed promoters in R6/2 mouse and human HD brain. Genome-wide analysis showed a novel chromatin signature for this mark. Reducing the levels of the H3...
ORGANISM(S): Mus musculus 
2013-07-18 | E-GEOD-48962 | biostudies-arrayexpress
UnknownMicrodeletion of target sites for insulator protein CTCF in a chromosome 11p15 imprinting center in Beckwith-Wiedemann syndrome and Wilms' tumor.
Not available
S-EPMC554791 | biostudies-literature
GenomicsTargeting H3K4 methylation as a therapeutic strategy for Huntington's disease (ChIP-seq)
Transcriptional dysregulation is an early feature of Huntington's disease (HD). We observed gene-specific changes in H3K4me3 at transcriptionally repressed promoters in R6/2 mouse and human HD brain. Genome-wide analysis showed a novel chromatin signature for this mark. Reducing the levels of the H3...
ORGANISM(S): Mus musculus 
2013-07-18 | E-GEOD-48960 | biostudies-arrayexpress
UnknownA Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.
Not available
S-EPMC23782 | biostudies-literature
UnknownReplication of twelve association studies for Huntington's disease residual age of onset in large Venezuelan kindreds.
Not available
S-EPMC2597910 | biostudies-literature
GenomicsExtensive changes in DNA methylation are associated with expression of mutant huntingtin [ChIP-seq]
The earliest stages of HuntingtonM-bM-^@M-^Ys disease are marked by changes in gene expression that are caused in an indirect and poorly understood manner by polyglutamine expansions in the huntingtin protein (HTT). To explore the hypothesis DNA methylation may be altered in cells expressing mutate...
ORGANISM(S): Mus musculus 
2013-01-24 | E-GEOD-43429 | biostudies-arrayexpress
TranscriptomicsExtensive changes in DNA methylation are associated with expression of mutant huntingtin [mRNA-seq]
The earliest stages of Huntington’s disease are marked by changes in gene expression that are caused in an indirect and poorly understood manner by polyglutamine expansions in the huntingtin protein (HTT). To explore the hypothesis DNA methylation may be altered in cells expressing mutated HTT, we ...
ORGANISM(S): Mus musculus 
2013-01-24 | E-GEOD-43431 | biostudies-arrayexpress
GenomicsExtensive changes in DNA methylation are associated with expression of mutant huntingtin [MeDIP-seq]
The earliest stages of Huntington’s disease are marked by changes in gene expression that are caused in an indirect and poorly understood manner by polyglutamine expansions in the huntingtin protein (HTT). To explore the hypothesis DNA methylation may be altered in cells expressing mutated HTT, we ...
ORGANISM(S): Mus musculus 
2013-01-24 | E-GEOD-43430 | biostudies-arrayexpress
GenomicsExtensive changes in DNA methylation are associated with expression of mutant huntingtin [RRBS]
The earliest stages of Huntington’s disease are marked by changes in gene expression that are caused in an indirect and poorly understood manner by polyglutamine expansions in the huntingtin protein (HTT). To explore the hypothesis DNA methylation may be altered in cells expressing mutated HTT, we ...
ORGANISM(S): Mus musculus 
2013-01-24 | E-GEOD-43432 | biostudies-arrayexpress
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