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TranscriptomicsDNA methylation data from pilocytic astrocytoma tumor samples and normal cerebellum controls
Pilocytic astrocytomas (PA) are the most common brain tumor in pediatric patients and can cause significant morbidity, including chronic neurological deficiencies. They are characterized by activating alterations in the mitogen-activated protein kinase (MAPK) pathway, but little else is known about ...
ORGANISM(S): Homo sapiens 
2013-06-12 | E-GEOD-44684 | biostudies-arrayexpress
TranscriptomicsGene expression data from pilocytic astrocytoma tumour samples and normal cerebellum controls
Pilocytic astrocytomas (PA) are the most common brain tumor in pediatric patients and can cause significant morbidity, including chronic neurological deficiencies. They are characterized by activating alterations in the mitogen-activated protein kinase (MAPK) pathway, but little else is known about ...
ORGANISM(S): Homo sapiens 
2013-06-12 | E-GEOD-44971 | biostudies-arrayexpress
TranscriptomicsMicroRNA sequence and expression analysis in breast tumors by deep sequencing
This SuperSeries is composed of the following subset Series: GSE29173: MicroRNA sequence and expression analysis in breast tumors by deep sequencing [miRNA sequence data] GSE29174: MicroRNA sequence and expression analysis in breast tumors by deep sequencing [mRNA expression array data] MicroRNAs (m...
ORGANISM(S): Homo sapiens 
2011-06-07 | E-GEOD-28884 | biostudies-arrayexpress
TranscriptomicsMethylation profiling data from medulloblastoma tumor samples
Smoothened (SMO)-inhibitors recently entered clinical trials for sonic-hedgehog driven medulloblastoma (SHH-MB). Clinical response appears highly variable. To understand the mechanism(s) of primary resistance and to identify pathways co-operating with aberrant SHH-signaling, we sequenced a large coh...
ORGANISM(S): Homo sapiens 
2014-09-02 | E-GEOD-49377 | biostudies-arrayexpress
TranscriptomicsMicroRNA sequence and expression analysis in breast tumors by deep sequencing [miRNA sequence data]
MicroRNAs (miRNAs) regulate many genes critical for tumorigenesis. We profiled miRNAs from 11 normal breast tissues, 17 non-invasive, 151 invasive breast carcinomas, and 6 cell lines by in-house-developed barcoded Solexa sequencing. miRNAs were organized in genomic clusters representing promoter-con...
ORGANISM(S): Homo sapiens 
2011-06-06 | E-GEOD-29173 | biostudies-arrayexpress
TranscriptomicsMicroRNA sequence and expression analysis in breast tumors by deep sequencing [mRNA expression array data]
MicroRNAs (miRNAs) regulate many genes critical for tumorigenesis. We profiled miRNAs from 11 normal breast tissues, 17 non-invasive, 151 invasive breast carcinomas, and 6 cell lines by in-house-developed barcoded Solexa sequencing. miRNAs were organized in genomic clusters representing promoter-con...
ORGANISM(S): Homo sapiens 
2011-06-07 | E-GEOD-29174 | biostudies-arrayexpress
Genomicsena-DATASET-DKFZ-IBIOS-01-08-2014-08:50:46:817-29 - samples
Low-coverage whole genome sequencing of sporadic schwannomatosis patients
EGAD00001000964 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-01-08-2014-08:47:40:399-28 - samples
Exome sequencing of sporadic schwannomatosis patients
EGAD00001000963 | EGA
GenomicsNext generation sequencing of sporadic schwannomatosis samples
Schwannomatosis (MIM #162091) is characterized by the development of multiple schwannomas without vestibular nerve involvement (which is a characteristic of neurofibromatosis type 2 - NF2). In an effort to detect novel genetic alterations predisposing to schwannomatosis, we sequenced eight tumor-blo...
EGAS00001000767 | EGA
TranscriptomicsRobust Molecular Classification of Ependymal Tumors Across All Anatomic Compartments
Ependymal tumors across age groups have been classified solely by histopathology. It is, however, commonly accepted that this classification has limited clinical utility based on its poor reliability. We aimed at establishing a reliable and reproducible molecular classification using DNA methylation...
ORGANISM(S): Homo sapiens 
2015-05-21 | E-GEOD-65362 | biostudies-arrayexpress
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