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TranscriptomicsMouse primary megakaryocytes, wild type & NF-E2p45-deficient
To identify p45 target genes, we conducted gene expression profiling with p45-null megakaryocytes cultured from E14.5 fetal liver. Many genes encoding membrane proteins and enzymes related to platelet function, including Txas, Glycoprotein 6 (Gp6) and Selectin P (Selp), were repressed in the absence...
ORGANISM(S): Mus musculus 
2010-03-22 | E-GEOD-15581 | biostudies-arrayexpress
ProteomicsProteome analysis of NanoMEDIC particles
CRISPR-Cas9 has tremendous potential as a therapeutic tool for treating human diseases. However, prolonged expression of the nuclease and gRNA from viral vectors in an in vivo context may cause off-target activity and immunogenicity. While extracellular vesicles have been recently demonstrated to be...
ORGANISM(S): Homo Sapiens (human) 
2020-01-30 | PXD014527 | JPOST Repository
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