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ProteomicsProfiling of the Helicobacter pylori redox switch HP1021 regulon using a multi-omics approach
The gastric human pathogen Helicobacter pylori has developed mechanisms to combat stress factors, including reactive oxygen species (ROS). Here, we present a comprehensive study on the redox switch protein HP1021 regulon combining transcriptomic, proteomic and DNA-protein interactions analyses. Our ...
ORGANISM(S): Helicobacter pylori J99 (Campylobacter pylori J99) 
2023-09-20 | PXD041978 | Pride
Glucose consumption Helicobacter pylori Hp1021 Oxidative stress 
TranscriptomicsCharacterization of the HP1021 regulon of Helicobacter pylori
The genome of the gastric pathogen Helicobacter pylori harbors a remarkably low number of regulatory genes, including three and five open reading frames encoding two-component histidine kinases and response regulators, respectively, which are putatively involved in transcriptional regulation. Inacti...
ORGANISM(S): Helicobacter pylori 
2010-07-01 | E-GEOD-5971 | biostudies-arrayexpress
GenomicsChIP-seq of Helicobacter pylori N6 wild-type and HP1021 deletion mutant under microaerophilic and aerobic conditions (optimal growth and oxidative stress conditions, respectively).
We performed DNA-protein interaction (ChIP-seq) analyses for Helicobacter pylori N6 wild-type (WT) and HP1021 deletion mutant (ΔHP1021::aphA-3) under oxidative stress (21% O2) and optimal microaerobic growth (5% O2) conditions. We detected 100 binding sites of HP1021 on the H. pylori N6 chromosome, ...
ORGANISM(S): Helicobacter pylori 
2023-09-23 | E-MTAB-13026 | biostudies-arrayexpress
TranscriptomicsCharacterization of the HP1021 regulon of Helicobacter pylori
The genome of the gastric pathogen Helicobacter pylori harbors a remarkably low number of regulatory genes, including three and five open reading frames encoding two-component histidine kinases and response regulators, respectively, which are putatively involved in transcriptional regulation. Inacti...
ORGANISM(S): Helicobacter pylori 
2007-04-01 | GSE5971 | GEO
UnknownHP1021 is a redox switch protein identified in Helicobacter pylori.
Not available
S-EPMC8266642 | biostudies-literature
UnknownProfiling of the Helicobacter pylori redox switch HP1021 regulon using a multi-omics approach.
Not available
S-EPMC10593804 | biostudies-literature
GenomicsChIP-seq of Helicobacter pylori N6 wild-type and HP1021 deletion mutant under microaerophilic and aerobic conditions (optimal growth and oxidative stress conditions, respectively).
ChIP-seq of Helicobacter pylori N6 wild-type and HP1021 deletion mutant under microaerophilic and aerobic conditions (optimal growth and oxidative stress conditions, respectively).
PRJEB62491 | ENA
UnknownAI-2 Induces Urease Expression Through Downregulation of Orphan Response Regulator HP1021 in Helicobacter pylori.
Not available
S-EPMC9010608 | biostudies-literature
TranscriptomicsRNA-seq of Helicobacter pylori N6 wild-type and HP1021 deletion mutant under microaerophilic and aerobic conditions (optimal growth and oxidative stress conditions, respectively)
We performed transcriptome (RNA-seq) analyses for Helicobacter pylori N6 wild-type (WT) and HP1021 deletion mutant (ΔHP1021::aphA-3) under oxidative stress and optimal microaerobic growth conditions. The expression of 411 genes was affected by oxidative stress in stressed wild-type cells (WTS) comp...
ORGANISM(S): Helicobacter pylori 
2023-09-23 | E-MTAB-13025 | biostudies-arrayexpress
GenomicsHelicobacter pylori
Characterization of the HP1021 regulon of Helicobacter pylori
PRJNA97443 | ENA
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