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TranscriptomicsCXCL12 Production by Early Mesenchymal Progenitors is Required for Hematopoietic Stem Cell Maintenance
Hematopoietic stem cells (HSCs) primarily reside in the bone marrow where signals generated by stromal cells regulate their self-renewal, proliferation, and trafficking. Endosteal osteoblasts and perivascular stromal cells including endothelial cells3, CXCL12-abundant reticular (CAR) cells, leptin-...
ORGANISM(S): Mus musculus 
2013-01-31 | E-GEOD-43613 | biostudies-arrayexpress
UnknownInduced fusion and aggregation of bacterial outer membrane vesicles: Experimental and theoretical analysis.
Not available
S-EPMC7487024 | biostudies-literature
UnknownA phase I study of the HDM2 antagonist SAR405838 combined with the MEK inhibitor pimasertib in patients with advanced solid tumours.
Not available
S-EPMC6354023 | biostudies-literature
TranscriptomicsXenoestrogen-induced epigenetic repression of non-coding microRNA genes in breast epithelial cells
Early exposure to xenoestrogens may predispose to breat cancer risk later in adult life. The long-lived, self-regenerating epithelial progenitor cells are more susceptible to these exposure injuries and transmit the injured memory throught epigenetic mechanisms to their differentiated progeny. We ha...
ORGANISM(S): Homo sapiens 
2012-04-15 | E-GEOD-16001 | biostudies-arrayexpress
UnknownComprehensive Genomic Profiling of 282 Pediatric Low- and High-Grade Gliomas Reveals Genomic Drivers, Tumor Mutational Burden, and Hypermutation Signatures.
Not available
S-EPMC5728033 | biostudies-literature
UnknownAssociation of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis.
Not available
S-EPMC5840029 | biostudies-literature
UnknownIdentification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesity
Not available
S-SCDT-10_1038-S44321-025-00216-4 | biostudies-other
ProteomicsEvaluating the Performance of the Astral Mass Analyzer for Quantitative Proteomics Using Data Independent Acquisition
We evaluate the quantitative performance of the newly released Asymmetric Track Lossless (Astral) analyzer. Using data independent acquisition, the Orbitrap Astral mass spectrometer quantifies 5 times more peptides per unit time than state-of-the-art Orbitrap mass spectrometers, which have long been...
ORGANISM(S): Homo Sapiens 
PXD042704 | panorama
UnknownAPOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO): Design and Rationale.
Not available
S-EPMC7056919 | biostudies-literature
UnknownShort-term progression of interstitial lung disease in systemic sclerosis predicts long-term survival in two independent clinical trial cohorts.
Not available
S-EPMC6311344 | biostudies-literature
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