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TranscriptomicsExpression evolution in gene groups: Inferring non-neutral regulatory change in pathways from transcriptional profiling data
We profiled the transcriptomes of four Saccharomyces species, as well as pairwise hybrids between three of the species with S. cerevisiae For pairwise comparisons between Saccharomyces cerevisiae and each of S. paradoxus, S. mikatae, and S. bayanus, we performed 3'-end RNA-seq on RNA from each paren...
ORGANISM(S): Saccharomyces cerevisiae x Saccharomyces mikatae 
2013-10-21 | E-GEOD-38875 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in Malaysian and Wine/European yeast isolates
Comparative-genomic studies have reported widespread variation in levels of gene expression within and between species. In the vast majority of cases, the phenotypic and evolutionary relevance of regulatory change is unknown. We haveu sed a wild Malaysian population of S. cerevisiae as a testbed in ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-10-25 | E-GEOD-51645 | biostudies-arrayexpress
TranscriptomicsCharacterization of an Oxaliplatin Sensitivity Predictor in a preclinical Murine Model of Colorectal Cancer
Despite advances in contemporary chemotherapeutic strategies, long term survival still remains elusive for patients with metastatic colorectal cancer. A better understanding of the molecular markers of drug sensitivity to match therapy with patient is needed to improve clinical outcomes. In this stu...
ORGANISM(S): Homo sapiens 
2012-02-17 | E-GEOD-28691 | biostudies-arrayexpress
UnknownPharmacokinetics of infigratinib and its active metabolites in Chinese patients with advanced gastric cancer harboring FGFR2 gene amplification.
Not available
S-EPMC11604989 | biostudies-literature
TranscriptomicsIKKe coordinates invasion and metastasis
IKKe was identified previously as a breast cancer oncogene and was associated with poor clinical outcome in ovarian cancer. In order to elucidate functional roles of IKKe, we used microarray analysis to identify genes changed upon IKKe shRNA knockdown and compared with genes affected in ovarian canc...
ORGANISM(S): Homo sapiens 
2012-11-16 | E-GEOD-42320 | biostudies-arrayexpress
TranscriptomicsTranscriptional impact of removing H2A.Z
We profiled the strand-specific transcriptome of Saccharomyces cerevisiae lacking SWR1 and HTZ1 and compared it to the wild-type transcriptome 3'-end RNA-seq was performed on RNA from Saccharomyces cerevisiae wild-type and swr1 htz1 strains (two biological replicates each)
ORGANISM(S): Saccharomyces cerevisiae 
2016-06-01 | E-GEOD-46535 | biostudies-arrayexpress
UnknownqTAG: An adaptable plasmid scaffold for CRISPR-based endogenous tagging
Not available
S-SCDT-10_1038-S44318-024-00337-5 | biostudies-other
UnknownUnraveling the start element and regulatory divergence of core promoters across the domain bacteria.
Not available
S-EPMC12641261 | biostudies-literature
TranscriptomicsFezf2 overexpression in murine cortical progenitors in vivo
Corticospinal motor neurons (CSMN) are one specialized class of cortical excitatory neurons, which connect layer Vb of the cortex to the spinal cord. a master transcription factor –Forebrain expressed zinc finger 2 (Fezf2) – has been identified that is necessary for the fate specification of CSMN. F...
ORGANISM(S): Mus musculus 
2014-07-06 | E-GEOD-56451 | biostudies-arrayexpress
TranscriptomicsTime-course leaf expression data from Populus deltoides
We conducted micro-array analysis to quantify the global transcriptome variations in leaves through the course of the year allowing for identification of changing developmental signals. We used RNA samples from pre-formed and mature leaves in the upper crown of a sexually mature Populus deltoides tr...
ORGANISM(S): Populus deltoides 
2011-05-23 | E-GEOD-24349 | biostudies-arrayexpress
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