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TranscriptomicsEffect of LPS and LPS-binding protein treatment on RAW 264.4 cells
All samples were gathered from mouse RAW 264.7 cells (macrophages). Control total RNA was extracted from untreated RAW 264.7 cells cultured for either 1, 2, 4, 8, 16 or 48 hours. Test total RNA was extracted from lipopolysaccharide (100ng/ml) and lipopolysaccharide-binding protein (100pM) treated RA...
ORGANISM(S): Mus musculus 
2004-03-04 | E-GEOD-1098 | biostudies-arrayexpress
TranscriptomicsMajor Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands
We examined the major patterns of changes in gene expression in mouse splenic B cells in response to stimulation with 33 single ligands for 0.5, 1, 2, and 4 h. We found that ligands known to directly induce or costimulate proliferation, namely, anti-IgM (anti-Ig), anti-CD40 (CD40L), LPS, and, to a l...
ORGANISM(S): Mus musculus 
2004-12-08 | E-GEOD-2050 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression profiling of hepatocellular carcinomas in B6C3F1 mice induced by Ginkgo biloba extract by gavage for two years
Ginkgo biloba leaf extract (GBE) has been used for centuries in traditional Chinese medicine and today is used as an herbal supplement for various indications such as improving neural function, anti-oxidant and anti-cancer effects. As part of the herbal supplement industry, these compounds are large...
ORGANISM(S): Mus musculus 
2012-12-07 | E-GEOD-29813 | biostudies-arrayexpress
TranscriptomicsRAW264.7 cells were treated with KDO, IFN beta and 8Br
RAW 264.7 cells were stimulated with KDO (100 ng/ml), IFN-β (300 pM) and/or 8-Br 100 μM. These ligands were applied individually or in combination with KDO for 60 min and 120 min. Total RNA was extracted using TriPure (Roche) following its protocol. Keywords: designed RAW 264.7 cells were stimulat...
ORGANISM(S): Mus musculus 
2008-06-28 | E-GEOD-11449 | biostudies-arrayexpress
TranscriptomicsElevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: Implications for prostate cancer progression
Background: Aldo-keto reductase (AKR) 1C family member 3 (AKR1C3), one of four identified human AKR enzymes, catalyzes steroid, prostaglandin, and xenobiotic metabolism. In the prostate, AKR1C3 is up-regulated in localized and advanced prostate adenocarcinoma, and is associated with prostate cance...
ORGANISM(S): Homo sapiens 
2010-08-10 | E-GEOD-20956 | biostudies-arrayexpress
UnknownAdmixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X.
Not available
S-EPMC2679192 | biostudies-literature
UnknownGenome-wide association study and multi-ancestry meta-analysis identify common variants associated with carotid artery intima-media thickness.
Not available
S-EPMC12047956 | biostudies-literature
UnknownGenetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study.
Not available
S-EPMC4522594 | biostudies-literature
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