Sort   by:  
 Page size 
TranscriptomicsIdentification of markers associated with deregulated hTERT during HPV-medaited transformation
Although high-risk human papillomavirus (HPV) infection plays a major role in the development of cervical cancer, additive oncogenic events are involved as well. One key event involves increased activity of telomerase resulting from a deregulated expression of its catalytic subunit hTERT. Our previo...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-8288 | biostudies-arrayexpress
Transcriptomicshuman hTERT-RPE1 cell spheroid : Control siRNA transfected vs. YAP1 siRNA transfected
Transcriptional profiling of human hTERT-RPE1 cell spheroids comparing Control siRNA transfected hTERT-RPE1 cell spheroids with those transfected with YAP1 siRNA. Two-condition experiment, Control siRNA vs.YAP1 siRNA hTERT-RPE1 cell spheroids. Biological replicates: 1 Control siRNA, 1YAP1 siRNA tran...
ORGANISM(S): Homo sapiens 
2015-02-01 | E-GEOD-54146 | biostudies-arrayexpress
TranscriptomicsShort-term molecular consequences of chromosome mis-segregation for genome stability
RNA-sequencing samples from DMSO or Reversine treated hTERT RPE-1 cells. Reversine treated cells were further divided in those still able to continue to proliferate and those that got arrested. Cells were analyzed to generate panel in Figure 6d and e, and Extended Data Figure 8g and h.
ORGANISM(S): Homo sapiens 
2023-01-31 | E-MTAB-12537 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells
Extra chromosome copies markedly alter the physiology of eukaryotic cells, but the underlying reasons are not well understood. We created human trisomic and tetrasomic cell lines and determined the quantitative changes in their genome, transcriptome and proteome in comparison to their diploid counte...
ORGANISM(S): Homo sapiens 
2012-09-12 | E-GEOD-39768 | biostudies-arrayexpress
GenomicsNutlin-3a induced changes in the transcriptome of HCT116 and RPE-1 cells
Nutlin-3a induced changes in the transcriptome of HCT116 and RPE-1 cells
PRJNA895054 | ENA
TranscriptomicsNutlin-3a induced changes in the transcriptome of HCT116 and RPE-1 cells
RNA-seq from HCT116 and RPE-1 hTERT cells treated with Nutlin-3a or DMSO control
ORGANISM(S): Homo sapiens 
2024-09-18 | GSE216720 | GEO
UnknownConstruction of a human hTERT RPE-1 cell line with inducible Cre for editing of endogenous genes.
Not available
S-EPMC8864296 | biostudies-literature
TranscriptomicsProfiling of chromatin deposition bias in RPE-1 cells using Double-click-seq
We used double-click-seq method to profile chromatin deposition bias in RPE-1 cells. Untreated wild-type, p53 knock-out and several treatments (hydroxyurea, ATR inhibitor, curaxin) and their combinations were profiled for characterizing assymetry during DNA replication.
ORGANISM(S): Homo sapiens 
2021-10-04 | E-MTAB-8624 | biostudies-arrayexpress
UnknownEndogenous oncogenic KRAS expression increases cell proliferation and motility in near-diploid hTERT RPE-1 cells.
Not available
S-EPMC11234024 | biostudies-literature
GenomicsSingle-cell ORF perturbation screening of an enriched viral microprotein library in hTERT RPE-1 cells using 10x Genomics Flex fixed-RNA profiling
Single-cell ORF perturbation screening of an enriched viral microprotein library in hTERT RPE-1 cells using 10x Genomics Flex fixed-RNA profiling
PRJNA1516028 | ENA
Sort   by:  
 Page size