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TranscriptomicsGene expression profiles of Lkb1 WT and KO hematopoietic stem cells (HSCs)
LKB1 encodes a Ser/Thr kinase and acts as an evolutionarily conserved sensor of cellular energy status in eukaryotic cells. LKB1 functions as the major upstream kinase to phosphorylate AMPK and 12 other AMPK-related kinases, which is required for their activation in many cellular contexts. Once acti...
ORGANISM(S): Mus musculus 
2010-12-01 | E-GEOD-24765 | biostudies-arrayexpress
TranscriptomicsGene expression profiles in human kidney cancer cells in response to FoxO1 or FoxO3 activation
The mammalian FoxO transcription factors - FoxO1, FoxO3, FoxO4 - function in the nucleus to direct transcription of specific gene targets governing cellular survival, proliferation, metabolism, differentiation and oxidative defense. Activation of PI3K by extracellular growth factors leads to AKT-med...
ORGANISM(S): Homo sapiens 
2011-10-20 | E-GEOD-23926 | biostudies-arrayexpress
ProteomicsMyocardial Mitochondrial Antiviral Signaling Protein Promotes Heart Ischemia-reperfusion Injury via RIG-I Signaling-proteomic sequencing
Myocardial ischemia-reperfusion injury (MIRI) is a life-threatening complication of myocardial infarcts, with inner mitochondrial membrane protein dysfunction involved in MIRI-induced heart injury. The role of outer mitochondrial membrane protein MAVS is unknown. Here we show that MAVS expression in...
ORGANISM(S): Mus Musculus 
2025-03-20 | PXD062097 |
ProteomicsMyocardial Mitochondrial Antiviral Signaling Protein Promotes Heart Ischemia-reperfusion Injury via RIG-I Signaling-mass spectrometry
Myocardial ischemia-reperfusion injury (MIRI) is a life-threatening complication of myocardial infarcts, with inner mitochondrial membrane protein dysfunction involved in MIRI-induced heart injury. The role of outer mitochondrial membrane protein MAVS is unknown. Here we show that MAVS expression in...
ORGANISM(S): Mus Musculus 
2025-03-20 | PXD062096 |
ProteomicsProteomics data of WHO I and WHO III meningiomas
Proteomics data of endothelial meningiomas, fibrous meningiomas and anaplastic meningiomas
ORGANISM(S): Homo Sapiens 
2022-03-17 | PXD032342 |
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