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GenomicsThe MLL3/MLL4 branch of the COMPASS family regulates H3K4 monomethylation at enhancers
Histone H3 lysine 4 (H3K4) can be mono-, di-, and trimethylated by members of the COMPASS (COMplex of Proteins ASsociated with Set1) family from yeast to human and these modifications can be found at distinct regions of the genome. Monomethylation of histone H3K4 (H3K4me1) is relatively more enriche...
ORGANISM(S): Homo sapiens 
2013-09-30 | E-GEOD-51176 | biostudies-arrayexpress
TranscriptomicsMultiple roles for LEC in initiation and elongation phases of snRNA gene transcription
The small nuclear RNA (snRNA) genes have been widely used as a model system for understanding transcriptional regulation due to unique aspects of their promoter structure, selectivity for either RNA Polymerase (Pol) II or III and a unique mechanism of termination that is tightly linked with the prom...
ORGANISM(S): Homo sapiens 
2013-08-08 | E-GEOD-47938 | biostudies-arrayexpress
GenomicsMLL4 (KMT2D) inactivating mutations lead to focal loss of H3K4me1/2 and deregulated gene expression in B cell lymphomas
We identified KMT2D target loci in OCI-LY7 by ChIPseq. KMT2D ChIPseq was carried out in the LY7 cell line (n=1).
ORGANISM(S): Homo sapiens 
2015-08-28 | E-GEOD-67314 | biostudies-arrayexpress
UnknownHigher reliability and validity of Wavelet-ALFF of resting-state fMRI: From multicenter database and application to rTMS modulation.
Not available
S-EPMC9875929 | biostudies-literature
TranscriptomicsMll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells
Promoters of many developmentally regulated genes, in the embryonic stem cell state, have a bivalent mark of H3K27me3 and H3K4me3, proposed to confer precise temporal activation upon differentiation. Although Polycomb repressive complex 2 is known to implement H3K27 trimethylation, the COMPASS famil...
ORGANISM(S): Mus musculus 
2013-08-11 | E-GEOD-48172 | biostudies-arrayexpress
UnknownReal-Time Evaluation of Helicobacter pylori Infection by Convolution Neural Network During White-Light Endoscopy: A Prospective, Multicenter Study (With Video).
Not available
S-EPMC10589579 | biostudies-literature
ProteomicsLysine 2-hyroxyisobutyrylome, acetylome and succinylome in prokaryotes
identification of lysine 2-hyroxyisobutyrylome, acetylome and succinylome in prokaryotes
ORGANISM(S): Proteus Mirabilis Atcc 29906 Escherichia Coli 
2019-04-04 | PXD013377 |
UnknownSimultaneous Recognition of Atrophic Gastritis and Intestinal Metaplasia on White Light Endoscopic Images Based on Convolutional Neural Networks: A Multicenter Study.
Not available
S-EPMC8337066 | biostudies-literature
TranscriptomicsH3K4me2 and gene expression profiling in control and KMT2D KD murine B220 cells
Define and compare H3K4me2 enrichment in murine B220 cells transduced with empty vector (ct) or KMT2D-shRNA. Compare gene expression by RNAseq in murine B220 cells transduced with empty vector (ct) or KMT2D-shRNA. Using H3K4me1/2 ChIPseq and RNAseq we profiled murine B220 purified cells from tumors ...
ORGANISM(S): Mus musculus 
2015-08-28 | E-GEOD-67291 | biostudies-arrayexpress
UnknownClinical profiling and prognosis of out-of-hospital cardiac arrest in ST-segment elevation myocardial infarction in an Asian population.
Not available
S-EPMC12723052 | biostudies-literature
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