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UnknownAssociation of Vitamin D Levels With Outcome in Patients With Melanoma After Adjustment For C-Reactive Protein.
Not available
S-EPMC4966337 | biostudies-literature
MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (NMR assay)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS640 | MetaboLights
TranscriptomicsMolecular signatures of peripheral blood mononuclear cells following chronic IFN-alpha: Relationship of OAS2 with Depression and Fatigue
Interferon (IFN)-alpha causes high rates of depression and fatigue, and is used to investigate the impact of innate immune cytokines on brain and behavior. However, little is known about transcriptional profiles of circulating immune cells during chronic IFN-alpha administration. Accordingly, genome...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-31187 | biostudies-arrayexpress
ProteomicsFrom plants to ants: Evaluating lipidomic changes in leaf-cutter ant fungus gardens
Leaf-cutter ants use fresh plant material to cultivate an obligate mutualistic fungus Leucoagaricus gongylophorus in specialized fungus gardens to access and transform nutrients from plant biomass that would otherwise be unavailable to the ants. Here, we evaluated the lipidomic differences between t...
ORGANISM(S): Environmental Samples <bacteria> (ncbitaxon:48479) 
2019-10-30 | MSV000084520 | MassIVE
UnknownβA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity.
Not available
S-EPMC7904954 | biostudies-literature
MetabolomicsNon-redundant cardiolipin synthase family proteins shape lipid composition and stress resilience in Bacteroides fragilis

Gut-resident bacteria must withstand membrane-disrupting stresses such as bile acids to persist in the intestinal environment. The Bacteroidota are a dominant phylum of the human gut microbiota. However, the genes responsible for synthesis of membrane lipids in this phylum remain relatively uncha...

2026-10-06 | MTBLS11891 | MetaboLights
TranscriptomicsTranscriptional profiling of pancreatic beta cells during maturation and with function-inactivating mutations
Islet β-cells from newborn mammals need a maturation process to become mature functional beta cells. The detailed molecular mechanisms were not completely understood. This study was designed to reveal the dynamic gene expression changes during pancreatic beta-cell maturation in postnatal mice. We al...
ORGANISM(S): Mus musculus 
2018-04-01 | E-MTAB-6615 | biostudies-arrayexpress
UnknownSensory neurons promote immune homeostasis in the lung.
Not available
S-EPMC10811756 | biostudies-literature
TranscriptomicsExpression analysis of a full Lsr locus knockout in Haemophilus influenzae strain CZ4126/02
Investigation of whole genome gene expression differences in a full (nine-gene) Lsr locus knockout strain compared to the wild-type strain (CZ4126/02). This Lsr mutant is unable to import the autoinducer-2 (AI-2) quorum sensing molecule nor mediate any potential LsrR-based transcriptional regulation...
ORGANISM(S): Haemophilus influenzae 
2012-10-19 | E-GEOD-41690 | biostudies-arrayexpress
TranscriptomicsExpression analysis of a full SlrV locus 1 knockout in Haemophilus influenzae strain PittII
Investigation of whole genome gene expression differences between a full (four-gene) SlrV locus 1 deletion compared to the WT PittII strain. Removal of the four SlrV genes (aka macrophage survival factors : ?msf) results in a competetive defect with the WT strain in in vitro biofilms and in the oti...
ORGANISM(S): Haemophilus influenzae PittII 
2015-06-23 | E-GEOD-70172 | biostudies-arrayexpress
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