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MetabolomicsDiallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
Diallyl disulfide (DADS), a garlic extract also known as allicin, has been reported to have numerous biological activities, including anticancer, antifungal, and inflammation-inhibiting activities, among others. Although many studies have assessed whether DADS can treat Candida albicans infec...
2022-05-03 | MTBLS3750 | MetaboLights
TranscriptomicsGene expression analysis in control and HIF-2 alpha deficient murine lung endothelial cells under hypoxia
Journal : Blood. 2009 Jul 9;114(2):469-77. Epub 2009 May 13. Title : Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis. Authors : Skuli N, Liu L, Runge A, Wang T, Yuan L, Patel S, Iruela-Arispe L, Simon MC, Keith B. Abstract : Hyp...
ORGANISM(S): Mus musculus 
2009-07-15 | E-GEOD-16067 | biostudies-arrayexpress
ProteomicsIdentification of the novel function of adipocyte plasma membrane associated protein (APMAP) in gestational diabetes mellitus by proteomic analysis of omental adipose tissues
Gestational diabetes mellitus (GDM) is considered as the early stage of type 2 diabetes mellitus. In this study, we compared the demographic and clinical data between six GDM and six NGT (healthy controls) and found the HOMA-IR was increased in GDM. Previously, many researches had proved that omenta...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080798 | MassIVE
ProteomicsCSF quantitative proteomics reveals potential diagnostic biomarker of pediatric bacterial meningitis
In this study, we performed label-free based CSF quantitative proteomics to identify and analyze the differentially expressed proteins among bacterial meningitis, viral meningitis and hospital controls (children with benign intracranial hypertension). Compared with viral meningitis and hospital cont...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD026663 | Pride
Csf Bacterial meningitis Diagnostic biomarker 
TranscriptomicsRNA-seq analysis of crypt samples isolated from the small intestine of Bach2 KO and control mice
Epithelial regeneration is critical for barrier maintenance and organ function after intestinal injury. Here, we found that Bach2 deficiency promotes the intestinal epithelial cell proliferation during homeostasis and facilitates the crypt regeneration after irradiation, resulting in a reduction of ...
ORGANISM(S): Mus musculus 
2021-01-12 | E-MTAB-9865 | biostudies-arrayexpress
ProteomicsProteome of root from Gossypium barbadense infected by Verticillium
In this study, two kinds of island cotton materials with different resistances of Verticillium dahliae were used for Verticillium dahliae infection, the proteomic was used to detect all the protein expression levels in the roots of the two kinds of cotton, and the spectronaut pulsar x software was s...
ORGANISM(S): Gossypium Barbadense 
PXD017527 |
ProteomicsTargets Identification of NPB by the combined use of DARTS technology and proteomics
We found that the stability of OorD protein increased with the combination of DARTS technology and mass spectrometry identification.This result suggests that OorD may be a target of NPB.
ORGANISM(S): Helicobacter Pylori G27 
2024-11-26 | PXD058270 |
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