Sort   by:  
 Page size 

Beyond motor neuron degeneration, homozygous mutations in the survival motor neuron 1 (SMN1) gene cause multiorgan and metabolic defects in patients with spinal muscular atrophy (SMA). However, the precise biochemical features of these alterations and the age of onset in the brain and peripheral ...

2023-11-27 | MTBLS8784 | MetaboLights
Tet-mediated DNA oxidation is a new type of epigenetic modification in mammals and its role in the regulation of cell fate transition remains poorly understood. Here, we derive mouse embryonic fibroblasts (MEFs) deleted in all three Tet genes and examine their capability to be reprogrammed into iPS ...
ORGANISM(S): Mus musculus 
Wild type, elg1d, pol30f, and pol30f elg1d cells were arrested in G1 and synchronously released in the presence of HU for 30 or 60 minutes. Genomic DNA was extracted, amplified, and hybridized to a whole genome tiling microarray. Replicated regions were identified as peaks that exhibit increased co...
ORGANISM(S): Saccharomyces cerevisiae 
Methanothermobacter thermautotrophicus is a model thermophilic hydrogenotrophic methanogen. The life and survival of M. thermautotrophicus is highly influenced by the availability of nutrients and temperature. To learn about adaptation mechanisms evolved by the archaea to cope with drastic temperatu...
ORGANISM(S): Methanobacterium 
2018-10-02 | PXD006685 | Pride
Sort   by:  
 Page size