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TranscriptomicsS phase and HU profiles in wild-type and mutant cells
Total S phase was measured for wild-type cells undergoing meiS and mitS. Early replication origins were mapped in mitS in wild-type cells, and in meiS for wild-type, sml1 delete, rec8 delete and spo11 delete cells. Comparative genome hybridization was used to measure the kinetics and final extent of...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-18 | E-GEOD-35662 | biostudies-arrayexpress
TranscriptomicsRec8 guides canonical Spo11 distribution along yeast meiotic chromosomes
Spo11-mediated DNA double strand breaks (DSBs) that initiate meiotic recombination are temporally and spatially controlled. The meiotic cohesin Rec8 has been implicated in regulating DSB formation, but little is known about the features of their interplay. To shed light on this point, we investigate...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-18 | E-GEOD-8422 | biostudies-arrayexpress
UnknownAssociation of MYO9B gene polymorphisms with inflammatory bowel disease in Chinese Han population.
Not available
S-EPMC4064092 | biostudies-literature
TranscriptomicsRNA-seq analysis of gene expression during and after exposure to hydroxyurea in WT and mec1 cells in Saccharomyces cerevisiae
We previously demonstrated that inactivation of the replication checkpoint via a mec1 mutation led to chromosome breakage at replication forks initiated from virtually all origins of replication, after transient exposure to hydroxyurea (HU), an inhibitor of ribonucleotide reductase. Furthermore, we...
ORGANISM(S): Saccharomyces cerevisiae 
2015-01-12 | E-GEOD-63516 | biostudies-arrayexpress
UnknownHippocampal PPARδ Overexpression or Activation Represses Stress-Induced Depressive Behaviors and Enhances Neurogenesis.
Not available
S-EPMC4772271 | biostudies-literature
TranscriptomicsSeparation of DNA replication from the assembly of break-competent meiotic chromosomes
The meiotic cell division reduces the chromosome number from diploid to haploid to form gametes for sexual reproduction. Although much progress has been made in understanding meiotic recombination and the two meiotic divisions, the processes leading up to recombination, including the prolonged pre-m...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-14 | E-GEOD-35667 | biostudies-arrayexpress
TranscriptomicsExpression data from shoot bases of rice seedling after gravistimulation
Upper and lower parts (flanks) of rice (Oryza sativa sp. japonica) shoot bases at 0.5 h and 6 h after gravistimulation was used for expression analysis in control and gravistimulated samples.Targets from biological replicates of both control and gravistimulated samples were generated and expression ...
ORGANISM(S): Oryza sativa Japonica Group 
2011-09-01 | E-GEOD-31834 | biostudies-arrayexpress
UnknownThe Spin-Orbit Effect on the Electronic Structures, Refractive Indices, and Birefringence of X2PO4I (X = Pb, Sn, Ba and Sr): A First-Principles Investigation.
Not available
S-EPMC11013657 | biostudies-literature
TranscriptomicsBreak-Seq of DNA double stranded breaks in Saccharomyces cerevisiae WT and mec1 cells after exposure to hydroxyurea
We previously demonstrated that inactivation of the replication checkpoint via a mec1 mutation led to chromosome breakage at replication forks initiated from virtually all origins of replication, after transient exposure to hydroxyurea (HU), an inhibitor of ribonucleotide reductase. Furthermore, we...
ORGANISM(S): Saccharomyces cerevisiae 
2015-01-12 | E-GEOD-58808 | biostudies-arrayexpress
MetabolomicsDetermination of Abundant Metabolite Matrix Adducts Illuminates the Dark Metabolome of MALDI-Mass Spectrometry Imaging Datasets
Spatial metabolomics using mass spectrometry imaging (MSI) is a powerful tool to map hundreds to thousands of metabolites in biological systems. One major challenge in MSI is the annotation of m/z values, which is substantially complicated by background ions introduced throughout the c...
2021-06-15 | MTBLS954 | MetaboLights
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