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ProteomicsAberrant NAD+ metabolism underlies Zika virus-induced microcephaly
ZIKV-infection during pregnancy can cause microcephaly in newborns, yet the underlying mechanisms remain largely unexplored. Here, we reveal extensive and large-scale metabolic reprogramming events in ZIKV-infected mouse brains. We perform a multi-omics study comprising transcriptomics, proteomics, ...
ORGANISM(S): Mus Musculus 
2021-06-18 | PXD026814 |
ProteomicsProteomics analyses reveal potential therapeutic strategies for HCM
Proteomics was performed to facilitate the understanding of the metabolic alterations in HCM patients from proteinlevel
ORGANISM(S): Homo sapiens (Human) 
2022-03-22 | PXD032097 | Pride
Human Hcm Heart tissue Therapeutic strategies 
ProteomicsDelaying aging and enhancing repair of the aged CNS myelin by β-NMN requires SIRT2
Myelin aging is a driving force of CNS aging, and age-dependent declined efficiency of remyelination caused by impaired differentiation capacity of aged oligodendrocyte precursor cell (OPC) is a major cause of demyelinated diseases. Revealing how differentiation capacity of aged OPC is affected meta...
ORGANISM(S): Rattus Norvegicus 
2020-10-18 | PXD022046 |
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