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GenomicsH3K27me3 ChIP-seq experiment in fruitfly testis somatic gonadal cells
In many metazoans, germ cells are separated from somatic lineages early in development and maintain their identity throughout life. Here we show that a Polycomb group (PcG) component, Enhancer of Zeste [E(z)] H3K27me3-specific methyltransferase, maintains germline identity in Drosophila adult testes...
ORGANISM(S): Drosophila melanogaster 
2014-05-02 | E-GEOD-53238 | biostudies-arrayexpress
TranscriptomicsExpression changes in Tetrahymena thermophila TRX1 and EZL2 gene knockouts and after hydroxyurea (HU) treatment
12 genome-wide microarrays to investigate the Tetrahymena thermophila gene expression changes in TRX1 and EZL2 gene knockout and hydroxyurea (HU) treatment conditions. For the TRR1 knockout (KO) condition, wild type (WT427) cells and TRX1 KO cells were cultured using 1XSPP, 30 degrees, 100 rpm shaki...
ORGANISM(S): Tetrahymena thermophila 
2013-09-04 | E-GEOD-44990 | biostudies-arrayexpress
TranscriptomicsMapping Epigenomic Type-Specific Differences Occurring During Hematopoiesis
Formation of the blood from self-renewing hematopoietic stem cells to terminal lineages necessarily involves epigenomic modifications of the genome to control regulator and signature gene expression. By analysing the global expression profiles of hematopoietic stem cells (HSCs), in vivo differentiat...
ORGANISM(S): Homo sapiens 
2013-03-25 | E-GEOD-39229 | biostudies-arrayexpress
UnknownPhosphorylation Regulation of a Histone-like HU Protein from Deinococcus radiodurans.
Not available
S-EPMC9900698 | biostudies-literature
UnknownWhole genome sequencing and structural variations provide insights into the body size traits of Hu sheep.
Not available
S-EPMC12328574 | biostudies-literature
UnknownBacteriophage protein Gp46 is a cross-species inhibitor of nucleoid-associated HU proteins.
Not available
S-EPMC8892312 | biostudies-literature
UnknownGenomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep.
Not available
S-EPMC12499457 | biostudies-literature
GenomicsH2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-renewal and Differentiation
Chromatin modifications have been implicated in the self-renewal and differentiation of embryonic stem cells (ESCs). However, the function of histone variant H2A.Z in ESCs remains unclear. We show that H2A.Z is highly enriched at promoters and enhancers and is required for both efficient self-renewa...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-34483 | biostudies-arrayexpress
UnknownDiscovery of Novel Resistance Mechanisms of Vibrio parahaemolyticus Biofilm against Aminoglycoside Antibiotics.
Not available
S-EPMC10135303 | biostudies-literature
UnknownPredicting potential distribution of Ziziphus spinosa (Bunge) H.H. Hu ex F.H. Chen in China under climate change scenarios.
Not available
S-EPMC8855015 | biostudies-literature
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