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Fatty acid transport protein 4 (FATP4) is an acyl-CoA synthetase that is required for normal permeability barrier in mammalian skin. FATP4 (SLC27A4) mutations cause ichthyosis prematurity syndrome, a nonlethal disorder. In contrast, Fatp4-/- mice die neonatally from a defective barrier. H...
2021-07-15 | MTBLS1138 | MetaboLights
Metastatic relapse of breast cancer and other tumor types usually occurs several years after surgical resection of the primary tumor. Early dissemination of tumor cells followed by an extended period of dormancy is thought to explain this prevalent clinical behavior. By using a gain-of-function retr...
ORGANISM(S): Homo sapiens 
This study was designed to explore the role of miRNA-146a (miR-146a) and its target genes in the endothelial cells. In this study we have demonstrated that lipopolysaccharide (LPS) induced upregulation of miR-146a in the human umbilical vein endothelial cells (HUVEC) and the induction was blocked by...
ORGANISM(S): Homo sapiens 
In our research, applying a two-dimensional differential in gel electrophoresis (2D-DIGE) and the tandem mass spectrometry (MS/MS) method to investigate the differential expression of proteins of rats' cortex in the sham group, 3 day post sipnal cord transection, 14 day post sipnal cord transection,...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-09 | PXD017900 | Pride
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