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UnknownRapid identification of chemical profiles in vitro and in vivo of Huan Shao Dan and potential anti-aging metabolites by high-resolution mass spectrometry, sequential metabolism, and deep learning model.
Not available
S-EPMC11518704 | biostudies-literature
ProteomicsA novel Traditional Chinese Medicine, Ramulus Mori (Sangzhi) alkaloids ameliorates glucose metabolism accompanied by the modulation of gut microbiota and ileal inflammatory damage in type 2 diabetic KKAy mice
The novel Traditional Chinese Medicine Ramulus Mori (Sangzhi) alkaloid tablets (SZ-A) are approved by The China National Medical Products Administration for the treatment of type 2 diabetes mellitus (T2DM). However, the extensive pharmacological characteristics and the underlying mechanism are unkno...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD024241 | Pride
Ramulus mori (sangzhi) alkaloids  type 2 diabetes  gut microbiome  ileal damage  inflammation 
UnknownMorus alba L. (Sangzhi) Alkaloids Promote Insulin Secretion, Restore Diabetic β-Cell Function by Preventing Dedifferentiation and Apoptosis.
Not available
S-EPMC8927674 | biostudies-literature
UnknownTreatment Patterns and Glycaemic Control Between 2015 and 2019 in Tianjin, China: A Real-World Study of Adults with Type 2 Diabetes.
Not available
S-EPMC11759750 | biostudies-literature
UnknownNew anti-diabetic drug Morus alba L. (Sangzhi) alkaloids (SZ-A) improves diabetic nephropathy through ameliorating inflammation and fibrosis in diabetic rats.
Not available
S-EPMC10289017 | biostudies-literature
ProteomicsAnalysis of protein expression changes in patients with prediabetes using high-throughput proteomics
Objective: This study aimed to explore the mechanisms of early-onset T2DM by analyzing proteomic changes at different stages of glucose metabolism. Methods: A total of 40 individuals undergoing routine physical health examinations between December 2016 and April 2017 were enrolled. Subjects were di...
ORGANISM(S): Homo Sapiens 
2022-10-19 | PXD035367 |
UnknownIntegration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of <i>L.</i> (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism in Diabetic Rats.
Not available
S-EPMC12355231 | biostudies-literature
UnknownNonmuscle Myosin II is Required for Larval Shell Formation in a Patellogastropod.
Not available
S-EPMC8851382 | biostudies-literature
TranscriptomicsGene expression and alternative splicing data from human cartilage endplate-derived stem cells
Low back pain (LBP) is one of the most prevalent conditions which need medical advice and result in chronic disabilities. Degenerative disc disease (DDD) is a common reason for LBP. A lot of researchers think that CEP degeneration play critical roles in the initiation and development of DDD. In rece...
ORGANISM(S): Homo sapiens 
2015-12-21 | E-GEOD-63897 | biostudies-arrayexpress
MetabolomicsRabbit plasma metabolomic analysis of Nitroproston: a multi target natural prostaglandin based-drug (Untargeted study)
INTRODUCTION: Nitroproston® is a novel multi-target drug bearing natural prostaglandin E2 (PGE2) and nitric oxide (NO)-donating fragments for treatment of inflammatory and obstructive diseases (i.e. asthma and obstructive bronchitis). OBJECTIVES: To investigate the effects of Nitroproston® adm...
2019-08-27 | MTBLS727 | MetaboLights
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