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TranscriptomicsTranscription profiling of mouse transgenic tumors driven by Her or Ras
previously published mouse data; Pubmed IDS: 12754511, 12839964 Experiment Overall Design: see Black, EP, et.al., Cancer Res. 2003 Jul 1;63(13):3716-23 and Huang, E., et.al. Nat Genet. 2003 Jun;34(2):226-30.
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3158 | biostudies-arrayexpress
ProteomicsA dataset describing a suite of novel antibody reagents for the RAS signaling network
RAS genes are frequently mutated in cancer and have for decades eluded effective therapeutic attack. The National Cancer Institute’s RAS Initiative has a focus on understanding pathways and discovering therapies for RAS-driven cancers. Part of these efforts is the generation of novel reagents to ena...
ORGANISM(S): Homo Sapiens 
2019-09-03 | PXD012604 | panorama
TranscriptomicsAutotoxicity mechanism of Oryza Sativa: Microarray analysis of rice plants in response to allelochemical ferulic acid
Autotoxicity plays an important mechanism in regulating plant productivity. Ferulic acid (FA) is phytotoxic and was identified in extracts and residues of rice plants as a candidate for rice allelochemicals. To help characterize the autotoxicity mechanism of rice, we present the first large-scale, t...
ORGANISM(S): Oryza sativa 
2013-07-22 | E-GEOD-34899 | biostudies-arrayexpress
TranscriptomicsTransport of influenza A virus neuraminidase to host cell surface and virus replication are regulated by ARHGAP21 and Cdc42
Influenza virus neuraminidase (NA), a type II transmembrane glycoprotein, is transported to the virus assembly site at the plasma membrane and is a major viral envelope component that plays a critical role in the release of progeny virions and in determination of host range restriction. Although sig...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-32878 | biostudies-arrayexpress
UnknownRNA G-quadruplex secondary structure promotes alternative splicing via the RNA-binding protein hnRNPF.
Not available
S-EPMC5769772 | biostudies-literature
TranscriptomicsPten loss and RAS/MAPK activation cooperate to promote EMT and prostate cancer metastasis initiated from stem/progenitor cells
PTEN loss or PI3K/AKT signaling pathway activation correlates with human prostate cancer progression and metastasis. However, in preclinical murine models, deletion of Pten alone fails to mimic the significant metastatic burden that frequently accompanies the end stage of human disease. To identify...
ORGANISM(S): Mus musculus 
2012-02-28 | E-GEOD-34839 | biostudies-arrayexpress
TranscriptomicsExpression profiles of cultured human epididymis cells reveal the functional diversity of caput, corpus and cauda regions.
Purpose: To compare the transcriptome profiles (RNA-seq) of cultured human epididymis cells and tissue from the caput, corpus and cauda regions of the human epididymis. Methods: Human epididymis tissue was obtained with Institutional Review Board approval from 3 patients (UC05, UC06, UC09, range: 22...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-72986 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast epithelia cells after 17-beta-estradiol induced malignant cell transformation
The estrogen-dependence of breast cancer has long been recognized, however, the role of 17β-estradiol (E2) in cancer initiation was not known until we demonstrated that it induces complete neoplastic transformation of the human breast epithelial cells MCF-10F. E2-treatment of MCF-10F cells progress...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5116 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of bovine IVF embryos revealed candidate genes and pathways involved in early embryonic development
Using microarrays, genome-wide RNA expression was profiled and compared for in vitro fertilization (IVF) - derived blastocysts and embryos undergoing degenerative development up to the same time point. Surprisingly similar transcriptomic profiles were found in degenerative embryos and blastocysts. N...
ORGANISM(S): Bos taurus 
2010-10-28 | E-GEOD-24936 | biostudies-arrayexpress
TranscriptomicsExpression analysis for nasopharyngeal carcinoma cell lines 5-8F
High metastatic nasopharyngeal carcinoma cell line 5-8F expression patterns. This study was done to detect genes expressed in NPC cell line 5-8F. The microarray analyses were done in a same batch. cells are cultured and harvested at two different time points.
ORGANISM(S): Homo sapiens 
2009-12-10 | E-GEOD-15921 | biostudies-arrayexpress
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