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ProteomicsRBM39 organizes an m⁶A-dependent silencing complex to degrade Tat mRNA and maintain HIV-1 latency
Given the pivotal role of Tat in HIV-1 latency, we performed RNA pull-down assays in latently HIV-1-infected J-Lat 10.6 cells using biotinylated RNA probes (including a control RNA probe and a Tat-specific RNA probe) . Cell lysates were incubated with streptavidin agarose resin pre-bound to Tat RNA ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-31 | PXD064834 | Pride
Lc/ms Tat Rip J-lat 10.6 
MetabolomicsThe Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis

BACKGROUND: Manchurian walnut (Juglans mandshurica Maxim.) is a tree with multiple industrial uses and medicinal properties in the Juglandaceae family (walnuts and hickories). J. mandshurica produces juglone, which is a toxic allelopathic agent and has potential utilization value...

2022-05-18 | MTBLS3657 | MetaboLights
ProteomicsNUDCD3 deficiency disrupts V(D)J recombination to cause SCID/Omenn syndrome
Inborn errors of T cell development present a pediatric emergency in which timely curative therapy is informed by molecular diagnosis. In 9 affected patients across 3 consanguineous kindreds, we detected homozygosity for a single deleterious missense variant in the gene NudC domain containing 3 (NUD...
ORGANISM(S): Homo sapiens (Human) 
2024-09-27 | PXD035840 | Pride
Pulldown Nudcd3 Proteomics Omenn syndrome 
UnknownTotal synthesis of (+/-)-bipinnatin J.
Not available
S-EPMC2537461 | biostudies-literature
TranscriptomicsPyruvate fermentation vs Lactate-Sulfate
In order to obtain a global view of energy metabolism pathways of the sulfate-reducer Desulfovibrio vulgaris Hildenborough and the proteins involved therein whole-genome microarrays were used to compare the transcriptional response of cells grown with hydrogen/sulfate, pyruvate/sulfate, lactate/thio...
ORGANISM(S): Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough 
2008-05-31 | E-GEOD-8015 | biostudies-arrayexpress
TranscriptomicsAcetone stress response in Desulfovibrio vulgaris
Desulfovibrio vulgaris has been studied extensively for its potential in the bioremediation of heavy metals and radionuclides. Hydrocarbons and solvents, as frequent environmental co-contaminants, have been reported to inhibit microbial activities and thereby pose a limitation on bioremediation effi...
ORGANISM(S): Desulfovibrio vulgaris str. Hildenborough 
2009-08-08 | E-GEOD-5569 | biostudies-arrayexpress
TranscriptomicsEthanol stress response in Desulfovibrio vulgaris
Desulfovibrio vulgaris has been studied extensively for its potential in the bioremediation of heavy metals and radionuclides. Hydrocarbons and solvents, as frequent environmental co-contaminants, have been reported to inhibit microbial activities and thereby pose a limitation on bioremediation effi...
ORGANISM(S): Desulfovibrio vulgaris str. Hildenborough 
2010-06-24 | E-GEOD-7489 | biostudies-arrayexpress
TranscriptomicsPyruvate vs Lactate as electron donor in Sulfate reduction
In order to obtain a global view of energy metabolism pathways of the sulfate-reducer Desulfovibrio vulgaris Hildenborough and the proteins involved therein whole-genome microarrays were used to compare the transcriptional response of cells grown with hydrogen/sulfate, pyruvate/sulfate, lactate/thio...
ORGANISM(S): Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough 
2008-05-31 | E-GEOD-8071 | biostudies-arrayexpress
TranscriptomicsThiosulfate vs Sulfate as electron acceptor in Sulfate reduction
In order to obtain a global view of energy metabolism pathways of the sulfate-reducer Desulfovibrio vulgaris Hildenborough and the proteins involved therein whole-genome microarrays were used to compare the transcriptional response of cells grown with hydrogen/sulfate, pyruvate/sulfate, lactate/thio...
ORGANISM(S): Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough 
2008-05-31 | E-GEOD-8072 | biostudies-arrayexpress
TranscriptomicsHydrogen vs Lactate as electron donor in Sulfate reduction
In order to obtain a global view of energy metabolism pathways of the sulfate-reducer Desulfovibrio vulgaris Hildenborough and the proteins involved therein whole-genome microarrays were used to compare the transcriptional response of cells grown with hydrogen/sulfate, pyruvate/sulfate, lactate/thio...
ORGANISM(S): Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough 
2008-05-31 | E-GEOD-8037 | biostudies-arrayexpress
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