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ProteomicsThe critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network
MLKL, as the executor of necroptosis and a critical factor in the inflammation, has been shown to be associated with the progression of hemorrhagic stroke. Studies identified MLKL is a promoting factor in this process, suggesting its potential as a therapeutic target to mitigate post-hemorrhagic str...
ORGANISM(S): Mus Musculus 
2024-09-27 | PXD056595 |
ProteomicsA proteomic landscape of mouse tissues' macrophages
proteome of LPS-stimulated macrophages in Il18-knockout mouse' liver and lung. proteome of LPS-stimulated macrophages in widetype mouse' liver and lung.
ORGANISM(S): Mus musculus (Mouse) 
2022-10-26 | PXD021657 | Pride
Mouse macrophage lc-ms/ms 
ProteomicsProteomic Analysis of Lysine lactylation in adipose tissue of HIIT mice
This project carried out a quantitative study of the target proteins that are lactylated and regulated by lactate levels in iWAT of HIIT mice. In order to ensure a high degree of credibility of the results, we quantitatively analyzed the changes in protein lactylation in three groups. Modification s...
ORGANISM(S): Mus <genus> 
2023-08-29 | PXD044919 |
ProteomicsProteomic analysis reveals key differences between squamous cell carcinomas and adenocarcinomas across multiple tissues
To explore the biological insights into squamous cell carcinoma (SCC) derived from different organs, we reported a deep proteomic analysis of 333 SCCs of 17 organs and 69 adenocarcinomas (ACs) of 7 organs. Proteomic comparison between pan-SCCs and pan-ACs identifies distinguishable pivotal pathways,...
ORGANISM(S): Homo Sapiens 
2022-05-19 | PXD033794 |
ProteomicsA proteomic landscape of macrophage in mouse tissues
Macrophages, locating in essentially all tissues, are critical for innate immune responses and involved in the tissue homeostasis. Distinct macrophages populations in different tissues exhibited diverse gene expressions and biological processes. Previous studies have accessed the molecular signature...
ORGANISM(S): Mus Musculus 
2022-10-28 | PXD021583 |
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