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UnknownTwelve Chinese patent medicines combined with conventional medicine for the treatment of functional dyspepsia: a network meta-analysis.

Background

This study systematically evaluates the clinical efficacy and safety of 12 Chinese Patent Medicines (CPMs) combined with conventional Western medicine (CWM) in treating Functional Dyspepsia (FD), aiming to provide robust evidence for optimizing treatment strategies.

Methods

S-EPMC12741128 | biostudies-literature
UnknownSimvastatin Improves Behavioral Disorders and Hippocampal Inflammatory Reaction by NMDA-Mediated Anti-inflammatory Function in MPTP-Treated Mice.
The cognitive function impairment may be related to the inflammation of the hippocampus in Parkinson's disease. Simvastatin can play a positive role in Parkinson's disease. The purpose of this study was to investigate whether simvastatin could improve behavioral disorders, especially depression, anx...
S-EPMC11448790 | biostudies-literature
UnknownA Precision Microbiome Approach Using Sucrose for Selective Augmentation of Staphylococcus epidermidis Fermentation against Propionibacterium acnes.
Acne dysbiosis happens when there is a microbial imbalance of the over-growth of Propionibacterium acnes (P. acnes) in the acne microbiome. In our previous study, we demonstrated that Staphylococcus epidermidis (S. epidermidis, a probiotic skin bacterium) can exploit glycerol fermentation to produce...
S-EPMC5133870 | biostudies-literature
ProteomicsSynthetic lethal combinations targeting PLK1-CBX8-GPX4 axis with BRAF and EGFR inhibition in BRAF V600E colorectal cancer
Metastatic BRAFV600E colorectal cancer (CRC) confers poor prognosis and run into a bottleneck in the current treatment strategies. To identify regulatory pathways independent of the MAPK pathway in BRAFV600E CRC, we performed CRISPR-Cas9 screening, and and find targeting glutathione peroxidase 4 (GP...
ORGANISM(S): Homo Sapiens 
2024-11-25 | PXD058213 |
ProteomicsIdentification of ciliary protein interactome during senescence
Despite the importance of cellular senescence in human health, how damaged cells undergo senescence remains vague. We have previously shown that the translocation of a ciliary protein FBF1 to nucleus is essential for senescence induction in stressed cells. However, how dose FBF1 translocate from cil...
ORGANISM(S): Homo sapiens (Human) 
2024-08-19 | PXD045355 | Pride
Primary cilia Senescence 
ProteomicsProteomic and phosphoproteomic analyses for HT-29
Metastatic BRAFV600E colorectal cancer (CRC) confers poor prognosis and run into a bottleneck in the current treatment strategies. To identify regulatory pathways independent of the MAPK pathway in BRAFV600E CRC, we performed CRISPR-Cas9 screening, and and find targeting glutathione peroxidase 4 (GP...
ORGANISM(S): Homo sapiens (Human) 
2025-02-28 | PXD058218 | Pride
Cbx8 Phosphoproteomic Proteomic Plk1 
UnknownEarly-life exposure to polypropylene nanoplastics induces neurodevelopmental toxicity in mice and human iPSC-derived cerebral organoids.
Nanoplastics (NPs) are emerging environmental pollutants that pose growing concerns due to their potential health risks. However, the effects of inhaled NP exposure during pregnancy on fetal brain development remain poorly understood. In this study, we investigated the impact of maternal exposure to...
S-EPMC12210689 | biostudies-literature
UnknownLess invasive surfactant administration versus endotracheal surfactant instillation followed by limited peak pressure ventilation in preterm infants with respiratory distress syndrome in China: study protocol for a randomized controlled trial.

Background

Less invasive surfactant administration (LISA) is a way of giving surfactant without endotracheal intubation and has shown to be promising in reducing the incidence of bronchopulmonary dysplasia (BPD) in preterm infants. However, the mechanism underlying its beneficial effect and ...
S-EPMC7289227 | biostudies-literature
ProteomicsProteomic analysis of YexiangB and the OsMKK3 mutant line
TMT-based quantitative proteomic analysis of YexiangB and the OsMKK3 mutant line to obtain regulated proteins
ORGANISM(S): Oryza Sativa 
2022-11-09 | PXD038056 |
ProteomicsData-independent acquisition-based quantitative proteomics analysis reveals dynamic network profiles during the macrophage inflammatory response.
Understanding of the molecular regulatory mechanisms underlying the inflammatory response isincomplete, especially with respect to the global proteomic response to microbial infection. Data-independent acquisition (DIA)-based quantitative proteomic analysis has been widely applied inproteomics resea...
ORGANISM(S): Mus Musculus 
2019-12-09 | PXD016668 |
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