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Metastatic BRAFV600E colorectal cancer (CRC) confers poor prognosis and run into a bottleneck in the current treatment strategies. To identify regulatory pathways independent of the MAPK pathway in BRAFV600E CRC, we performed CRISPR-Cas9 screening, and and find targeting glutathione peroxidase 4 (GP...
ORGANISM(S): Homo Sapiens 
2024-11-25 | PXD058213 |
Despite the importance of cellular senescence in human health, how damaged cells undergo senescence remains vague. We have previously shown that the translocation of a ciliary protein FBF1 to nucleus is essential for senescence induction in stressed cells. However, how dose FBF1 translocate from cil...
ORGANISM(S): Homo sapiens (Human) 
2024-08-19 | PXD045355 | Pride
Metastatic BRAFV600E colorectal cancer (CRC) confers poor prognosis and run into a bottleneck in the current treatment strategies. To identify regulatory pathways independent of the MAPK pathway in BRAFV600E CRC, we performed CRISPR-Cas9 screening, and and find targeting glutathione peroxidase 4 (GP...
ORGANISM(S): Homo sapiens (Human) 
2025-02-28 | PXD058218 | Pride
TMT-based quantitative proteomic analysis of YexiangB and the OsMKK3 mutant line to obtain regulated proteins
ORGANISM(S): Oryza Sativa 
2022-11-09 | PXD038056 |
Understanding of the molecular regulatory mechanisms underlying the inflammatory response isincomplete, especially with respect to the global proteomic response to microbial infection. Data-independent acquisition (DIA)-based quantitative proteomic analysis has been widely applied inproteomics resea...
ORGANISM(S): Mus Musculus 
2019-12-09 | PXD016668 |
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