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ProteomicsMudPIT analyses of FLAG-DYRK1A and FLAG-Controls affinity-purified from cytoplasmic extracts of HEK293 cells
Approximately 10E9 cells for each cell line (FLAG-DYRK1A, FLAG-DYRK1A-K188R, and FLAG-controls) were collected and washed with PBS. Cells were swollen for 15 minutes in hypertonic buffer (Buffer A: 10 mM Hepes pH 7.9, 1.5 mM MgCl2, 10 mM KCl, 0.5 mM DTT) freshly supplemented with protease inhibitor ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-23 | MSV000085815 | MassIVE
TranscriptomicsTranscription profiling of rat eye eQTL experiment
We used expression quantitative trait locus mapping in the laboratory rat (Rattus norvegicus) to gain a broad perspective of gene regulation in the mammalian eye and to identify genetic variation relevant to human eye disease. Of >31,000 gene probes represented on an Affymetrix expression microarray...
ORGANISM(S): Rattus norvegicus 
2008-06-14 | E-GEOD-5680 | biostudies-arrayexpress
UnknownA Clade-Specific Arabidopsis Gene Connects Primary Metabolism and Senescence.
Not available
S-EPMC4940393 | biostudies-literature
TranscriptomicsThe Lung Microbiome of HIV-infected Pneumonia Patients in Sub-Saharan Africa
Sub-Saharan Africa represents 69% of the total number of individuals living with HIV infection worldwide and 72% of AIDS deaths globally. Pulmonary infection is a common and frequently fatal complication, though little is known regarding the lower airway microbiome composition of this population. Ou...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-52791 | biostudies-arrayexpress
MetabolomicsThe Bardet-Biedl protein Bbs1 controls photoreceptor outer segment protein and lipid composition

Summary

Primary cilia are key sensory organelles whose dysfunction leads to ciliopathy disorders such as Bardet-Biedl syndrome (BBS). Retinal degeneration is common in ciliopathies, since the outer segments (OSs) of photoreceptors are highly specialized primary cilia. BBS...

2022-02-18 | MTBLS4013 | MetaboLights
TranscriptomicsTranscription profiling of human non anaplastic T-cell lymphoma
A ﾑCartes dﾒIdentite des Tumeursﾒ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | Affymetrix HG-U133 Plus 2.0 : 17 AITL biopsies, 2 AITL sorted cells, 16 PTCL NOS biopsies | The molecular alterations underlying the pathogenesis of angioimmunoblast...
ORGANISM(S): Homo sapiens 
2009-09-22 | E-TABM-783 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of human nasal NK/T-cell Lymphoma (8 tumor samples, 2 cell lines)
A ﾑCartes dﾒIdentite des Tumeursﾒ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net ) | Human genome-wide CIT-aCGH-V6-4.4K : 8 NKTCL biopsies, 2 NKTCL cell lines. Biopsies and cell lines of NK/T-cell lymphoma, nasal-type (NKTCL) were subject to combine...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-TABM-791 | biostudies-arrayexpress
Transcriptomics26 mouse embryonic stem cell , embryonic body cell, and colony-forming samples (affymetrix exon array)
Intragenic microRNAs (miRNAs), including both intronic and exonic miRNAs, accounting approximately 50% of total mammalian miRNAs. Previous studies showed that intragenic miRNAs are often co-expressed with their host genes, and thus it was believed that intragenic miRNAs and their host genes are deri...
ORGANISM(S): Mus musculus 
2011-03-02 | E-GEOD-27397 | biostudies-arrayexpress
Transcriptomics81 human leukemia samples (affymetrix exon array)
Intragenic microRNAs (miRNAs), including both intronic and exonic miRNAs, accounting approximately 50% of total mammalian miRNAs. Previous studies showed that intragenic miRNAs are often co-expressed with their host genes, and thus it was believed that intragenic miRNAs and their host genes are deri...
ORGANISM(S): Homo sapiens 
2011-03-02 | E-GEOD-27370 | biostudies-arrayexpress
TranscriptomicsExpression and CGHarray profiling of Hepatosplenic T-cell Lymphomas (10 tumor samples)
A Cartes dIdentite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | Affymetrix HG-U133 Plus 2.0 : 10 HSTL samples including biopsies (n=6), sorted tumor cells (n=3), cell line (n=1) | Agilent SurePrint G3 Human CGH Microarray 4x180K Arrays ...
ORGANISM(S): Homo sapiens 
2011-09-30 | E-MTAB-638 | biostudies-arrayexpress
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