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Systemic acquired resistance (SAR) is a plant defense response that provides resistance against a wide range of pathogens at the whole-plant level after a primary infection. In this study, we used a data independent acquisition (DIA) phosphoproteomics platform based on the high-resolution mass spect...
ORGANISM(S): Arabidopsis Thaliana 
2021-07-23 | PXD027512 |
In this project we discovered that CAP not only reduces joint swelling in arthritic model mice but also exhibits anti-inflammatory and antiproliferative effects on fibroblast-like synoviocytes (FLS). By synthesizing alkyne-tagged CAP probes and employing activity-based protein profiling (ABPP), we i...
ORGANISM(S): Homo Sapiens 
2024-11-07 | PXD057639 |
In this project we discovered that CAP not only reduces joint swelling in arthritic model mice but also exhibits anti-inflammatory and antiproliferative effects on fibroblast-like synoviocytes (FLS). By synthesizing alkyne-tagged CAP probes and employing activity-based protein profiling (ABPP), we i...
ORGANISM(S): Homo Sapiens 
2024-11-12 | PXD057819 |
The activity of 5’-adenosine monophosphate-activated protein kinase (AMPK) is inversely correlated with the cellular availability of glucose. When glucose levels are low, the glycolytic enzyme aldolase is not bound to fructose-1,6-bisphosphate (FBP) and, instead, signals to activate lysosomal AMPK. ...
ORGANISM(S): Oryctolagus Cuniculus 
2022-08-10 | PXD035968 |
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