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MetabolomicsMetabolomic assessment of acute cholestatic injuries induced by thioacetamide and by bile duct ligation, and the protective effects of Huang-Lian-Jie-Du-Decoction
Huang-Lian-Jie-Du-Decoction, a traditional Chinese formula, has been reported to protect liver from various injuries. Two cholestasis models of rats induced by thioacetamide and by bile duct ligation were established and treated with Huang-Lian-Jie-Du-Decoction. Nuclear Magnetic Resonance-based urin...
2016-06-08 | MTBLS149 | MetaboLights
TranscriptomicsTranscription profiling of spontaneously hypertensive and Sprague Dawley rat lung tissue from subjects exposed to sulfur dioxide and controls
Chronic obstructive pulmonary disease (COPD) is diagnosed by airway obstruction and underlies a group of ailments such as bronchitis, emphysema and often asthma; however, rodent models do not resemble human pathology. Because genetically predisposed spontaneously hypertensive (SH) rats display pheno...
ORGANISM(S): Rattus norvegicus 
2008-02-23 | E-GEOD-4702 | biostudies-arrayexpress
UnknownHistone Deacetylase 4 Inhibition Reduces Rotenone-Induced Alpha-Synuclein Accumulation via Autophagy in SH-SY5Y Cells.
Not available
S-EPMC10136981 | biostudies-literature
UnknownNew Metabolites from Aspergillus ochraceus with Antioxidative Activity and Neuroprotective Potential on H2O2 Insult SH-SY5Y Cells.
Not available
S-EPMC8746654 | biostudies-literature
TranscriptomicsNatural selection on cis and trans regulation in yeasts
Gene expression is regulated both by cis elements, which are DNA segments closely linked to the genes they regulate, and by trans activating factors, which are usually proteins capable of diffusing to unlinked genes. Understanding the patterns and sources of regulatory variation is crucial for under...
ORGANISM(S): Saccharomyces cerevisiae 
2010-04-02 | E-GEOD-20749 | biostudies-arrayexpress
UnknownBlumea chishangensis sp. nov. (Asteraceae: Inuleae) from Taiwan and new insights into the phylogeny of Blumea.
Not available
S-EPMC9276887 | biostudies-literature
UnknownA Fluorescent Probe for Imaging and Treating S-Nitrosation Stress in OGD/R Cells.
Not available
S-EPMC11939710 | biostudies-literature
TranscriptomicsSINGLET OXYGEN RESISTANT 1 links reactive electrophile signaling to singlet oxygen acclimation in Chlamydomonas reinhardtii
To identify components involved in the signal transduction and activation of the singlet oxygen-mediated response, a mutant selection was performed. This led to the isolation of the singlet oxygen resistant 1 (sor1) mutant, which is more tolerant to singlet oxygen-producing chemicals and shows a con...
ORGANISM(S): Chlamydomonas reinhardtii 
2012-04-03 | E-GEOD-33548 | biostudies-arrayexpress
MetabolomicsSulfadiazine Sodium Improves Dysfunctional Metabolomics in Toxoplasma gondii-infected Mice
Toxoplasma gondii is an obligate intracellular protozoan parasite that poses a severe threat to human health, especially those immune-compromised individuals. Sulfadiazine sodium (SDZ) is widely used for the treatment of human toxoplasmosis. However, systems biology researches on the therapeutic eff...
2019-06-18 | MTBLS852 | MetaboLights
UnknownSynthesis of Novel Baicalein Amino Acid Derivatives and Biological Evaluation as Neuroprotective Agents.
Not available
S-EPMC6832219 | biostudies-literature
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