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Proteomics4D-diaXLMS: Proteome-wide Four-Dimensional Data-Independent Acquisition Workflow for Cross-linking Mass Spectrometry
Cross-linking Mass Spectrometry (XL-MS) is a powerful tool for examining protein structures and interactions. Nevertheless, anal-ysis of low-abundance cross-linked peptides is often limited in data-dependent acquisition (DDA) mode due to its semistochastic nature. To address this issue, we introduce...
ORGANISM(S): Homo Sapiens Saccharomyces Cerevisiae 
PXD043282 |
TranscriptomicsRegulation of nucleosome landscape and transcription factor binding at enhancers by BRG1
Enhancers of transcription activate transcription via binding of sequence-specific transcription factors to their target sites in chromatin. In this report, we identify GATA1-bound enhancers genome-wide and find a global reorganization of the nucleosomes at these enhancers during differentiation of ...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-26501 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of HoxBlinc lncRNA downstream targets in mouse ESC-derived embryonic bodies
We find a new non-coding transcript associated with active HoxB locus, which we named HoxBlinc lncRNA. We report that HoxBlinc RNA specifies Flk1+ mesoderm and then promotes the development of HS/PCs and cardiomyocytes. To understand the molecular pathways reguated by HoxBlinc, we generate two dox...
ORGANISM(S): Mus musculus 
2015-11-11 | E-GEOD-74894 | biostudies-arrayexpress
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