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We performed RNA-seq to demonstrate that the epithelium of human pluripotent stem cell-derived human intestinal organoids is globally similar to the immature human epithelium and we utilize HIOs to investigate complex host-microbe interactions in this naive epithelium. RNA was isolated using the mir...
ORGANISM(S): Homo sapiens 
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
It was demonstrated that mice with eIF4E that cannot be activated by phosphorylation (S209A) produced extracellular matrix (ECM) less conducive to breast cancer tumor invasion and metastasis. To examine whether this could in part bedue to differences in the protein composition we analyzed the proteo...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD028953 | Pride

Humans interact with countless microorganisms in multiple environments. The Lung HIV Microbiome Project (LHMP) characterized the microbiome of the lung and respiratory tract. This effort provided initial data to develop further hypotheses addressing differences between HIV-infected and HIV-uninfe...

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