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UnknownDissecting the Underlying Pharmaceutical Mechanism of Chinese Traditional Medicine Yun-Pi-Yi-Shen-Tong-Du-Tang Acting on Ankylosing Spondylitis through Systems Biology Approaches.
Not available
S-EPMC5647417 | biostudies-literature
ProteomicsProteomics and metabolomics of different delivery modes in human pregnancy
This project investigates the impact of different delivery modes and labor on maternal and neonatal health by analyzing 40 participants, including 16 spontaneous vaginal deliveries (VD), 16 prelabor cesarean deliveries (CS), and 8 intrapartum cesarean sections (Intra_CS). Using label-free proteomics...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058131 | Pride
Proteomics   metabolomics   delivery modes 
ModelsQi2013 - IL-6 and IFN crosstalk model
Qi2013 - IL-6 and IFN crosstalk model This model [BIOMD0000000544] describes the crosstalk between IFN-gamma and IL-6 induced signalling; it aims to outline mechanisms and factors that may control the interaction between both signalling pathways, discussing a role of heterodimer formation in signa...
2024-09-02 | BIOMD0000000544 | BioModels
ModelsQi2013 - IL-6 and IFN crosstalk model (non-competitive)
Qi2013 - IL-6 and IFN crosstalk model (non-competitive) This model [BIOMD0000000543] describes the crosstalk between IFN-gamma and IL-6 induced signalling; it aims to outline mechanisms and factors that may control the interaction between both signalling pathways, discussing a role of heterodimer f...
2024-09-02 | BIOMD0000000543 | BioModels
TranscriptomicsTranscription profiling of human 48 clinical breast cancer arrays to perform statistical identification of gene association by CID in application of constructing ER regulatory network
A variety of high-throughput techniques are now available for constructing comprehensive gene regulatory networks in systems biology. In this study, we report a new statistical approach for facilitating in silico inference of regulatory network structure. The new measure of association, coefficient ...
ORGANISM(S): Homo sapiens 
2009-07-19 | E-GEOD-17041 | biostudies-arrayexpress
UnknownTransforming Endoscopic Image Classification with Spectrum-Aided Vision for Early and Accurate Cancer Identification.
Not available
S-EPMC12607974 | biostudies-literature
MetabolomicsBCAA insufficiency leads to premature ovarian insufficiency via ceramide-induced elevation of ROS (untargeted lipidomics)

Premature ovarian insufficiency (POI) is a disease featured by early menopause before 40 years of age, accompanied by an elevation of follicle-stimulating hormone. Though POI affects many aspects of women's health, its major causes remain unknown. Many clinical studies have shown that POI patient...

2024-09-26 | MTBLS6249 | MetaboLights
ProteomicsTargeting neddylation is a novel therapeutic strategy for lupus by reconstructing double negative T cell homeostasis
Systemic lupus erythematosus (SLE) is an autoimmune disorder with systemic inflammation, autoantibody accumulation and organ damage. The abnormalities of double-negative (DN) T cells are considered as an important commander of SLE. Neddylation, an important type of protein post-translational modific...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD045686 | Pride
Neddylation  ube2m  systemic lupus erythematosus (sle)  bim  double negative t cells (dn t cells)  apoptosis 
MetabolomicsBCAA insufficiency leads to premature ovarian insufficiency via ceramide-induced elevation of ROS (targeted metabolomics)

Premature ovarian insufficiency (POI) is a disease featured by early menopause before 40 years of age, accompanied by an elevation of follicle-stimulating hormone. Though POI affects many aspects of women's health, its major causes remain unknown. Many clinical studies have shown that POI patient...

2024-09-26 | MTBLS6267 | MetaboLights
ProteomicsThe proteome and phosphoproteome uncovers candidate proteins associated with vacuolar phosphate signal multipled by Vacuolar phosphate transporter1 (VPT1) in Arabidopsis
Plant vacuoles serve as the primary intracellular compartments for inorganic phosphate (Pi) storage. Passage of Pi across vacuolar membranes plays a critical role in buffering the cytoplasmic Pi level against fluctuations of external Pi and metabolic activities. To gain new insights into the protein...
ORGANISM(S): Arabidopsis Thaliana 
2023-03-08 | PXD040698 |
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