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ProteomicsHuman testicular biopsies iTRAQ proteomics
We collected testes biopsies from NOA (severe spermatogenic defects, no spermatids or sperm) and OA (normal spermatogenesis, tubular lumen obstruction) patients for iTRAQ proteomics analyses, to screen the genes for which the altered expression is involved in spermatogenic defects
ORGANISM(S): Homo sapiens (Human) 
2025-06-11 | PXD060811 | Pride
Human Noa Itraq Testicular biopsies 
ProteomicsTesticular Proteomics of PCM1 knockdown mice
Loss of pcm1 in mice disrupts the centrosome remodel and flagellar formation during spermatogenesis.
ORGANISM(S): Mus Musculus 
2024-04-03 | PXD051164 |
ProteomicsDenervated muscle promotes nerve regeneration via retrograde metabolic signaling, revising the neural-dominated view of neuromuscular interactions
Peripheral nerve injury causes muscle atrophy due to slow axonal regeneration, highlighting an unmet therapeutic need. Although neuromuscular interactions are classically viewed as unidirectionally nerve-dominated, we show that acutely denervated muscle (adMu) regulates nerve regeneration via a retr...
ORGANISM(S): Mus Musculus 
2025-12-02 | PXD071459 |
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