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TranscriptomicsTranscription profiling of human NOA patients identifies testicular gene expression profile for NOA patients, and ART3 as a genetic susceptibility gene for NOA
Infertility affects about one in six couples attempting pregnancy, with the man responsible in approximately half of the cases. Because the pathophysiology underlying azoospermia is not elucidated, most male infertility is diagnosed as idiopathic. Genome-wide gene expression analyses with microarra...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9210 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomic profiling of seminal plasma in nonobstructive azoospermia men: A noninvasive detection of spermatogenesis
Male factor infertility is involved in almost half of all infertile couples. Lack of the ejaculated sperm owing to testicular malfunction has been reported in 6-10% of infertile men, a condition named nonobstructive azoospermia (NOA). In this study, we investigated untargeted metabolomic profiling o...
2018-04-19 | MTBLS420 | MetaboLights
TranscriptomicsA testicular gene expression profile for NOA patients, and ART3 as a genetic susceptibility gene for NOA
Infertility affects about one in six couples attempting pregnancy, with the man responsible in approximately half of the cases. Because the pathophysiology underlying azoospermia is not elucidated, most male infertility is diagnosed as idiopathic. Genome-wide gene expression analyses with microarray...
ORGANISM(S): Homo sapiens 
2007-12-31 | GSE9210 | GEO
ProteomicsHuman testicular biopsies iTRAQ proteomics
We collected testes biopsies from NOA (severe spermatogenic defects, no spermatids or sperm) and OA (normal spermatogenesis, tubular lumen obstruction) patients for iTRAQ proteomics analyses, to screen the genes for which the altered expression is involved in spermatogenic defects
ORGANISM(S): Homo sapiens (Human) 
2025-06-11 | PXD060811 | Pride
Human Noa Itraq Testicular biopsies 
GenomicsRefining NOA diagnosis: a dual approach through immunostaining subclassification and metabolic markers in Sertoli cells
Refining NOA diagnosis: a dual approach through immunostaining subclassification and metabolic markers in Sertoli cells
PRJNA1445148 | ENA
TranscriptomicsRefining NOA diagnosis: a dual approach through immunostaining subclassification and metabolic markers in Sertoli cells
Background Non-obstructive azoospermia (NOA) is a leading cause of male infertility, affecting approximately 1% of men worldwide. Accurate pathological diagnosis and subclassification of NOA remain challenging due to the lack of reliable markers for germ cells (GCs) and Sertoli cells (SCs) within se...
ORGANISM(S): Homo sapiens 
2026-04-03 | GSE326372 | GEO
UnknownAuxin influx inhibitors 1-NOA, 2-NOA, and CHPAA interfere with membrane dynamics in tobacco cells.
Not available
S-EPMC2921198 | biostudies-literature
UnknownNOA: a novel Network Ontology Analysis method.
Not available
S-EPMC3141273 | biostudies-literature
UnknownNOA: a cytoscape plugin for network ontology analysis.
Not available
S-EPMC3722524 | biostudies-literature
UnknownDefects of microtubule cytoskeletal organization in NOA human testes.
Not available
S-EPMC9632130 | biostudies-literature
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