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ProteomicsDDA LC-MS/MS of reference human plasma and urine samples
Brief description of the data submitted: Three LC-MS/MS files acquired using Data Dependent Acquisition (DDA) for (1) NIST 1950 Frozen Human Plasma standard reference material subjected to reversed-phase chromatographic (RPC) metabolomic assay tailored for complex lipid separation; (2) plasma Long...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-04 | MSV000090642 | MassIVE
TranscriptomicsHPMCs treated with TNFalpha and IL-17A
Human mesothelial peritoneal cells from high grade serous ovarian carcinoma patients were subjected to TNFalpha, IL17-A and combination treatment.
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-13497 | biostudies-arrayexpress
TranscriptomicsscRNAseq of human omentum from high grade serous ovarian carcinoma patients, enriched for mesothelial cells
scRNAseq of HPMCs isolated ex vivo from 3 Patients. Targeted scRNASeq was applied using BD onco Panel with a additional genes. Purpose of the experiment was to characterize HPMC phenotype ex vivo and compare with the phenotype observed in RNAseq of HPMCs treated with IL17A and TNF.
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-13498 | biostudies-arrayexpress
MetabolomicsCXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury
Kidney injury is a common complication of severe disease. Here, we report that injuries of the zebrafish embryonal kidney are rapidly repaired by a migratory response in 2-, but not in 1-day-old embryos. Gene expression profiles between these two developmental stages identify cxcl12a and myca as can...
2018-10-11 | MTBLS723 | MetaboLights
MetabolomicsGNPS - DDA LC-MS/MS of reference human plasma and urine samples
Brief description of the data submitted: Three LC-MS/MS files acquired using Data Dependent Acquisition (DDA) for (1) NIST 1950 Frozen Human Plasma standard reference material subjected to reversed-phase chromatographic (RPC) metabolomic assay tailored for complex lipid separation; (2) plasma Long...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-04 | MSV000090642 | GNPS
UnknownControlling Coulomb correlations and fine structure of quasi-one-dimensional excitons by magnetic order.
Not available
S-EPMC11879853 | biostudies-literature
ProteomicsAsparagine hydroxylation of the UBA domain in Cezanne (OTUD7B)
by DUBs need to be tightly controlled. Here, we identify asparagine hydroxylation as a novel posttranslational modification involved in the regulation of Cezanne (OTUD7B), a DUB that controls key cellular functions and signaling pathways. We demonstrate that Cezanne is a substrate for FIH1- and oxyg...
ORGANISM(S): Homo sapiens (Human) 
2020-01-24 | PXD015216 | Pride
Otu7b Deubiquitinases Hydroxylation Cezanne 
ProteomicsUpregulation of USP18-ISG15 axis associates with protective immune responses and limited histopathology during SARS-CoV2 infection of the human lung
Investigating the intra-lung human immune responses to SARS-CoV-2, and how immune signatures temporally correlate to distinct histopathological manifestations of disease in the human lung, is not possible in human patients. While current non-human primate and rodent models have proven instrumental f...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2022-04-14 | PXD025851 | Pride
Lung fetal xenograft Humanized mice Sars-cov-2 Covid19 
TranscriptomicsDeep sequencing reveals abundant non-canonical onco-retroviral microRNAs in B-cell leukemia/lymphoma
Viral tumor models have significantly contributed to our understanding of oncogenic mechanisms. How transforming delta-retroviruses induce malignancy however remains poorly understood, especially as viral mRNA/protein are tightly silenced in tumors. Here, using deep sequencing of broad windows of sm...
ORGANISM(S): Ovis aries 
2013-01-24 | E-GEOD-42316 | biostudies-arrayexpress
ProteomicsDYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer
Highly malignant pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundant immunosuppressive and fibrotic tumor microenvironment (TME). Future therapeutic attempts therefore demand targeting of both compartments in order to be effective. We show here that Dual Specificity and Tyrosine...
ORGANISM(S): Mus Musculus 
2024-01-02 | MSV000093747 | MassIVE
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