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TranscriptomicsAge-dependent gene expression profiles after hepatic ischemia/reperfusion in mice
Experimental Design: 1. The goal of the experiment: Age-Dependent Gene Expression Profiles After Hepatic Ischemia/Reperfusion: Implications for the AP-1 and Ubiquitin-Proteosome Pathways 2. Brief description of the experiment: Hepatic ischemia/reperfusion (I/R) injury is a complication of liver surg...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-10654 | biostudies-arrayexpress
TranscriptomicsDivergent genome expression profiles during hepatic ischemia in young and adult mice
Experimental Design: 1. The goal of the experiment: Age-Related Genome Expression Profiles During Hepatic Ischemia 2. Brief description of the experiment: Hepatic ischemia/reperfusion (I/R) injury is a complication of liver surgery, transplantation and shock and differs with age. In the present stu...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-10652 | biostudies-arrayexpress
TranscriptomicsThe AHL- and BDSF-dependent quorum sensing systems control specific and overlapping sets of genes in Burkholderia cenocepacia H111
Quorum sensing in Burkholderia cenocepacia H111 involves two signalling systems that depend on different signal molecules, namely N-acyl homoserine lactones (AHLs) and the diffusible signal factor cis-2-dodecenoic acid (BDSF). Previous studies have shown that AHLs and BDSF control similar phenotypic...
ORGANISM(S): Burkholderia cenocepacia H111 
2012-11-01 | E-GEOD-41244 | biostudies-arrayexpress
TranscriptomicsThe IclR-family regulator BapR controls biofilms formation in B. cenocepacia H111
In Burkholderia cenocepacia H111, the large surface protein BapA plays a crucial role in the formation of highly structured communities, known as biofilms. We have recently demonstrated that Quorum sensing (QS) is necessary for the maximal expression of bapA. In this study we identify a protein from...
ORGANISM(S): Burkholderia cenocepacia H111 
2014-03-26 | E-GEOD-52769 | biostudies-arrayexpress
Transcriptomicss54 -dependent response to nitrogen limitation and virulence in Burkholderia cenocepacia H111
Members of the genus Burkholderia are versatile bacteria capable of colonizing highly diverse environmental niches. In this study, we investigated the global response of the opportunistic pathogen Burkholderia cenocepacia H111 to nitrogen limitation at the transcript and protein expression level. In...
ORGANISM(S): Burkholderia cenocepacia H111 
2015-04-29 | E-GEOD-66328 | biostudies-arrayexpress
UnknownDipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA-damage repair
Not available
S-SCDT-EMBOR-2021-54136V1 | biostudies-other
ProteomicsSRGAP1 controls small Rho GTPases to regulate podocyte foot process maintenance
Podocyte foot process effacement and proteinuria is a common and uniform consequence of glomerular injury. Previously it has been shown that small Rho GTPases (e.g. RAC1) are drivers of podocyte foot process effacement in glomerular diseases such as focal segmental glomerulosclerosis (FSGS). However...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-07-30 | MSV000085853 | MassIVE
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