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Kidney injury is a common complication of severe disease. Here, we report that injuries of the zebrafish embryonal kidney are rapidly repaired by a migratory response in 2-, but not in 1-day-old embryos. Gene expression profiles between these two developmental stages identify cxcl12a and myca as can...
2018-10-11 | MTBLS723 | MetaboLights
DallePezze2012 - TSC-independent mTORC2 regulation This model is described in the article: A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation. Dalle Pezze P, Sonntag AG, Thien A, Prentzell MT, Gödel M, Fischer S, Neumann-Haefelin E, Huber TB, B...
2024-09-02 | BIOMD0000000581 | BioModels
Diabetic kidney disease is a major complication in diabetes mellitus, and the most common reason for end-stage renal disease. Patients suffering from diabetes mellitus encounter glomerular damage by basement membrane thickening, and develop albuminuria. Subsequently, albuminuria can deteriorate the ...
2019-10-08 | MTBLS1093 | MetaboLights
Podocyte foot process effacement and proteinuria is a common and uniform consequence of glomerular injury. Previously it has been shown that small Rho GTPases (e.g. RAC1) are drivers of podocyte foot process effacement in glomerular diseases such as focal segmental glomerulosclerosis (FSGS). However...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-07-30 | MSV000085853 | MassIVE
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