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TranscriptomicsMicro-RNAs in Adult Rat Liver are Refractory to 19 Hours Dioxin Exposure
Dioxin-like chemicals are well-known for their ability to upregulate expression of numerous genes via the AH receptor (AHR). However, recent transcriptomic analyses in several laboratories indicate that dioxin-like chemicals or AHR genotype itself also can downregulate levels of mRNAs encoded by nu...
ORGANISM(S): Rattus norvegicus 
2007-08-15 | E-GEOD-8467 | biostudies-arrayexpress
TranscriptomicsCell-to-cell gene expression variability followed by reinforcement progressively segregates lineages in the early mouse embryo
Mammalian embryonic development begins with the specification and segregation of the two extra-embryonic lineages, trophectoderm and primitive endoderm, from the pluripotent embryonic lineage, the epiblast. To establish a map of epiblast (EPI) versus primitive endoderm (PrE) lineage segregation whic...
ORGANISM(S): Mus musculus 
2013-11-26 | E-MTAB-1681 | biostudies-arrayexpress
TranscriptomicsThirteen-week Nose-only Inhalation Exposures of Propylene Glycol Aerosols in Sprague Dawley Rats with a Lung Systems Toxicology Analysis.
Propylene glycol (PG) is a common carrier in e-vapor formulations and its properties have been extensively studied. In this 13-week subchronic nose-only inhalation study, Sprague Dawley rats were exposed to filtered air (sham control group), propylene glycol/water (PG/W; 90:10) or a propylene glycol...
ORGANISM(S): Rattus norvegicus 
2021-09-07 | E-MTAB-10006 | biostudies-arrayexpress
UnknownFeature selection by replicate reproducibility and non-redundancy.
Not available
S-EPMC11410923 | biostudies-literature
MetabolomicsGastropods and Insects Prefer Different Solanum dulcamara Chemotypes
Solanum dulcamara (Bittersweet nightshade) shows significant intraspecific variation in glycoalkaloid (GA) composition and concentration. We previously showed that constitutive differences in overall GA levels are correlated with feeding preference of the grey field slug (GFS; Deroceras reticulatum)...
2020-05-16 | MTBLS1132 | MetaboLights
UnknownHB-PLS: A statistical method for identifying biological process or pathway regulators by integrating Huber loss and Berhu penalty with partial least squares regression.
Not available
S-EPMC11524267 | biostudies-literature
TranscriptomicsXanthomonas campestris pv. Campestris 8004 far-red light irradiation and XccBphP overexpression transcriptional analysis
RNA isolation and RNA-Seq: Wild-type Xcc or pXccBphP strains were cultured in far-red light or dark conditions up to logarithmic phase (0.7 to 0.8 OD600) at 28C in PYM broth. Total bacterial RNA was isolated using the MasterPureTM RNA Purification Kit (Epicentre, Illumina). Samples corresponding to ...
ORGANISM(S): Xanthomonas campestris pv. campestris 
2016-12-03 | E-MTAB-4958 | biostudies-arrayexpress
MetabolomicsGlycoalkaloid composition explains variation in slug resistance in Solanum dulcamara
In natural environments, plants have to deal with a wide range of different herbivores whose communities vary in time and space. It is believed that the chemical diversity within plant species has mainly arisen from selection pressures exerted by herbivores. So far, the effects of chemical diversity...
2019-06-17 | MTBLS738 | MetaboLights
TranscriptomicsTAcKLE - Transcriptome Amplification and cDNA Labeling for Expression analysis
To characterize the properties and evaluate the performance of the TAcKLE procedure, a novel method providing effective transcriptome amplification for expression analyses on oligonucleotide microarrays, we performed 20 two-color hybridizations using self-spotted Operon 27k arrays. A single source o...
ORGANISM(S): Homo sapiens 
2004-08-13 | E-GEOD-1645 | biostudies-arrayexpress
TranscriptomicsHigh-fat diet induced gene expression changes in mouse retina may be prevented by introducing bilberries in diet
Obesity and diabetes associated visual impairment and vascular dysfunctions are increasing reasons for vision loss. The detailed mechanisms in these diseases are still largely unknown, but mice models have been useful to study these mechanisms and explore the detailed effects of potential compounds....
ORGANISM(S): Mus musculus 
2012-09-08 | E-GEOD-34154 | biostudies-arrayexpress
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